Objective. Technical advances in deep brain stimulation (DBS) are crucial to improve therapeutic efficacy and battery life. We report the potentialities and pitfalls of one of the first commercially available devices capable of recording brain local field potentials (LFPs) from the implanted DBS leads, chronically and during stimulation. The aim was to provide clinicians with well-grounded tips on how to maximize the capabilities of this novel device, both in everyday practice and for research purposes. Approach. We collected clinical and neurophysiological data of the first 20 patients (14 with Parkinson’s disease (PD), five with dystonia, one with chronic pain) that received the Percept™ PC in our centres. We also performed tests in a saline bath to validate the recordings quality. Main results. The Percept PC reliably recorded the LFP of the implanted site, wirelessly and in real time. We recorded the most promising clinically useful biomarkers for PD and dystonia (beta and theta oscillations) with and without stimulation. Furthermore, we provide an open-source code to facilitate export and analysis of data. Critical aspects of the system are presently related to contact selection, artefact detection, data loss, and synchronization with other devices. Significance. New technologies will soon allow closed-loop neuromodulation therapies, capable of adapting stimulation based on real-time symptom-specific and task-dependent input signals. However, technical aspects need to be considered to ensure reliable recordings. The critical use by a growing number of DBS experts will alert new users about the currently observed shortcomings and inform on how to overcome them.

目标。深部脑刺激 (DBS) 的技术进步对于提高治疗效果和电池寿命至关重要。我们报告了第一个能够从植入的 DBS 引线长期和刺激期间记录脑局部场电位 (LFP) 的商用设备之一的潜力和陷阱。目的是为临床医生提供有关如何在日常实践和研究目的中最大限度地发挥这种新型设备功能的充分依据的技巧。方法。我们收集了在我们中心接受 Percept™ PC 的前 20 名患者的临床和神经生理学数据（14 名患有帕金森病 (PD)，5 名患有肌张力障碍，1 名患有慢性疼痛）。我们还在盐水浴中进行了测试以验证录音质量。主要结果。Percept PC 以无线方式实时可靠地记录了植入部位的 LFP。我们记录了有和没有刺激的 PD 和肌张力障碍（β 和 θ 振荡）最有希望的临床有用的生物标志物。此外，我们提供了一个开源代码来促进数据的导出和分析。该系统的关键方面目前与联系人选择、人工制品检测、数据丢失以及与其他设备的同步有关。意义. 新技术将很快实现闭环神经调节疗法，能够根据实时特定症状和任务相关的输入信号调整刺激。但是，需要考虑技术方面以确保可靠的录音。越来越多的 DBS 专家的关键使用将提醒新用户当前观察到的缺点，并告知如何克服它们。