Denture wearers are advised to follow the protocol of using both mechanical and chemical hygiene methods. In this study, the in-vitro color stability of heat-cured, light-cured and newly developed pre-polymerized CAD/CAM acrylic resin base materials were evaluated after exposure to mechanical brushing and chemical denture cleansers. Two polymethyl methacrylate (PMMA) (heat-cured, and pre-polymerised CAD/CAM) and one urethane dimethacrylate based resin denture base material were subjected to mechanical brushing, followed by immersion in chemical denture cleansers (Corega, 5.25% Sodium hypochlorite (NaOCl), and 0.2% chlorhexidine gluconate (CHG)) and thermal-cycling to simulate one-year of normal prosthesis use. Baseline and final color measurements were determined and the difference in color was calculated using bench-top UV light visible spectrophotometer. The highest (29.691.84) and lowest (19.038.78) mean ΔE was observed with light-cured and CAD/CAM materials immersed in 0.2% CHG, respectively. Tukey’s post-hoc test showed that heat cured and light-cured resins immersed in either of the denture cleansers showed no significant differences (p>0.05) in the mean ΔE values. On the contrary, CAD/CAM materials immersed in either of the denture cleansers demonstrated significant differences in the mean ΔE values (p≤0.05). A statistically significant interaction between the combination of materials and denture cleansers (F=4.890; p=0.001) was observed. The color stability of the pre-polymerized CAD/CAM acrylic discs is comparatively better than the conventional acrylic resin materials. The changes in the color values of all the tested materials were above the clinically acceptable range, regardless of the type of denture cleanser used.

建议假牙佩戴者遵循使用机械和化学卫生方法的协议。在本研究中，体外在暴露于机械刷牙和化学义齿清洁剂后，评估了热固化、光固化和新开发的预聚合 CAD/CAM 丙烯酸树脂基材的颜色稳定性。两种聚甲基丙烯酸甲酯 (PMMA)（热固化和预聚合的 CAD/CAM）和一种氨基甲酸酯二甲基丙烯酸酯基树脂义齿基托材料进行机械刷牙，然后浸入化学义齿清洁剂（Corega，5.25% 次氯酸钠（NaOCl） ) 和 0.2% 葡萄糖酸氯己定 (CHG)）和热循环模拟一年的正常假肢使用。确定基线和最终颜色测量值，并使用台式紫外光可见分光光度计计算颜色差异。最高 (29.691.84) 和最低 (19.038.78) 平均 ΔE 在光固化和 CAD/CAM 材料浸入 0 中观察到。分别为 2% CHG。图基的事后测试表明，浸入任一义齿清洁剂中的热固化树脂和光固化树脂在平均 ΔE 值方面没有显着差异（p>0.05）。相反，浸入任一义齿清洁剂中的 CAD/CAM 材料在平均 ΔE 值上表现出显着差异 (p≤0.05)。观察到材料和义齿清洁剂的组合之间存在统计学上显着的相互作用（F=4.890；p=0.001）。预聚合的 CAD/CAM 亚克力盘的颜色稳定性相对优于传统的亚克力树脂材料。无论使用何种类型的义齿清洁剂，所有测试材料的颜色值变化均高于临床可接受的范围。