Cellulose nanocrystals (CNCs) are promising biomaterials, but their tendency to agglomerate when dried limits their use in several applications. Ultrasonication is commonly used to disperse CNCs in water, bringing enough energy to the suspension to break agglomerates. While the optimized parameters for sonication are now well defined for small volumes of low concentration CNC suspensions, a deeper understanding of the influence of the dispersing process is needed to work with larger volumes, at higher concentrations. Herein, rheology is used to define the distribution and dispersion states upon ultrasonication of a 3.2 wt% CNC suspension. After considering the importance of the measurement sampling volume, the behavior of a more concentrated suspension (6.4 wt%) is examined and compared with a never-dried suspension of the same concentration to validate the dispersion state.

纤维素纳米晶体 (CNC) 是有前途的生物材料，但它们在干燥时容易结块，限制了它们在多种应用中的应用。超声波处理通常用于将 CNCs 分散在水中，为悬浮液带来足够的能量以破坏团块。虽然现在已经为小体积的低浓度 CNC 悬浮液定义了优化的超声处理参数，但需要更深入地了解分散过程的影响，以便在更高浓度下使用更大的体积。在此，流变学用于定义 3.2 wt% CNC 悬浮液超声处理后的分布和分散状态。在考虑了测量采样体积的重要性之后，更浓缩的悬浮液的行为（6.