An expedient three-component reaction for the synthesis of acenaphtho[1',2':4,5]pyrrolo[2,3-d]pyrimidine, (hydropyrimidinyl) acenaphtho[1',2':4,5]pyrrolo[2,3-d]pyrimidine, and phenanthro[9,10-b]pyrimido[4,5-e][1,4]oxazine is described. The desired products were obtained in good to high yields. This work has the advantages of convenient operation, mild reaction conditions, simple workup, and provides an entry point to fused heterocyclic structures.

Graphic abstract

中文翻译：

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一锅三组分反应合成苊并[1',2':4,5]吡咯并[2,3-d]嘧啶衍生物

合成苊并[1',2':4,5]吡咯并[2,3- d ]嘧啶、(氢嘧啶基)苊[1',2':4,5]吡咯并[2]的一种方便的三组分反应,3- d ]嘧啶和菲[9,10- b ]嘧啶并[4,5- e ][1,4]恶嗪被描述。以良好至高产率获得所需产物。该工作具有操作方便、反应条件温和、后处理简单等优点，为稠合杂环结构的研究提供了一个切入点。

图形摘要