Childrenwith acute lymphoblastic leukemia (ALL) suffer a litany of chemotherapy-induced side effects. Constipation secondary to vinca alkaloids, psychological stressors, and opioid use are common issues for children newly diagnosed with leukemia. This study investigated the morbidity associated with constipation including infections, mucositis, and healthcare utilization in hospitalized children with ALL receiving induction chemotherapy.

中文翻译：

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美国儿童医院便秘对急性淋巴细胞白血病的二次影响

患有急性淋巴细胞白血病 (ALL) 的儿童会遭受一系列化疗引起的副作用。继发于长春花生物碱、心理压力源和阿片类药物的便秘是新诊断为白血病的儿童的常见问题。本研究调查了接受诱导化疗的 ALL 住院儿童与便秘相关的发病率，包括感染、粘膜炎和医疗保健利用。