The last two decades have witnessed tremendous progress in the development of microfluidic chips that generate micrometer- and nanometer-scale materials. These chips allow precise control over composition, structure, and particle uniformity not achievable using conventional methods. These microfluidic-generated materials have demonstrated enormous potential for applications in medicine, agriculture, food processing, acoustic, and optical meta-materials, and more. However, because the basis of these chips' performance is their precise control of fluid flows at the micrometer scale, their operation is limited to the inherently low throughputs dictated by the physics of multiphasic flows in micro-channels. This limitation on throughput results in material production rates that are too low for most practical applications. In recent years, however, significant progress has been made to tackle this challenge by designing microchip architectures that incorporate multiple microfluidic devices onto single chips. These devices can be operated in parallel to increase throughput while retaining the benefits of microfluidic particle generation. In this review, we will highlight recent work in this area and share our perspective on the key unsolved challenges and opportunities in this field.

中文翻译：

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扩大基于微流控液滴的材料合成的吞吐量：回顾近期进展和展望

在过去的二十年里，在产生微米级和纳米级材料的微流控芯片的开发方面取得了巨大进展。这些芯片允许对成分、结构和颗粒均匀性进行精确控制，这是使用传统方法无法实现的。这些微流体生成的材料在医学、农业、食品加工、声学和光学超材料等方面的应用显示出巨大的潜力。然而，由于这些芯片性能的基础是它们对微米级流体流动的精确控制，它们的操作仅限于由微通道中多相流动的物理特性决定的固有的低吞吐量。这种对吞吐量的限制导致材料生产率对于大多数实际应用来说太低了。然而近年来，通过设计将多个微流体设备整合到单个芯片上的微芯片架构，在应对这一挑战方面取得了重大进展。这些设备可以并行操作以增加吞吐量，同时保留微流体粒子生成的好处。在这篇评论中，我们将重点介绍该领域的最新工作，并分享我们对该领域未解决的主要挑战和机遇的看法。