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Association between Periodontitis and Carotid Artery Calcification: A Systematic Review and Meta-Analysis
BioMed Research International ( IF 3.246 ) Pub Date : 2021-09-06 , DOI: 10.1155/2021/3278351
Wenxuan Wang 1 , Zhenghao Yang 1 , Yue Wang 1 , Hongyu Gao 1 , Yan Wang 1 , Qiong Zhang 1
Affiliation  

Recent studies have supported the relationship between periodontitis and carotid artery calcification (CAC), but still uncertain. This systematic review is aimed at evaluating the association between periodontitis and CAC. The search was conducted in four electronic databases: PubMed, EMBASE, Web of Science, and The Cochrane Library, supplemented by checking references of included articles and related review articles. Eligibility assessment and data extraction were conducted independently. The quality assessment and publication bias analysis were performed. The association between periodontitis and CAC was presented in odd ratio (OR) with 95% confidence interval (CI). Additional outcomes included the percentage of alveolar bone loss in CAC versus non-CAC. Twelve studies were included, and 10 were performed quantity analysis. Periodontitis with secure definition (, ) and insecure definition (, ) was associated with CAC. And a higher average percentage of alveolar bone loss (; ) was also observed in CAC patients compared to non-CAC patients. No significant publication bias was found. The results of this systematic review and meta-analysis revealed a significant relationship between periodontitis and CAC.

中文翻译:

牙周炎与颈动脉钙化的关系:系统评价和荟萃分析

最近的研究支持牙周炎与颈动脉钙化(CAC)之间的关系,但仍不确定。本系统评价旨在评估牙周炎和 CAC 之间的关联。检索是在四个电子数据库中进行的:PubMed、EMBASE、Web of Science 和 Cochrane 图书馆,并辅以检查纳入文章和相关综述文章的参考文献。资格评估和数据提取是独立进行的。进行了质量评估和发表偏倚分析。牙周炎和 CAC 之间的关联以奇数比 (OR) 和 95% 置信区间 (CI) 表示。其他结果包括 CAC 与非 CAC 中牙槽骨丢失的百分比。纳入了 12 项研究,其中 10 项进行了数量分析。, )和不安全的定义 (, )与 CAC 相关联。并且牙槽骨丢失的平均百分比更高(; )与非 CAC 患者相比,在 CAC 患者中也观察到。未发现显着的发表偏倚。这项系统评价和荟萃分析的结果揭示了牙周炎和 CAC 之间的显着关系。
更新日期:2021-09-06
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