Objective

To report a unique case and literature review of post COVID-19 vaccination associated transverse myelitis and with abnormal MRI findings.

Background

Coronavirus disease have been reported to be associated with several neurological manifestations such as stroke, Guillain-Barré syndrome, meningoencephalitis amongst others. There are only a few reported cases of transverse myelitis with the novel coronavirus (n-CoV-2). Here, we identify a post COVID-19 vaccination patient diagnosed with acute transverse myelitis.

Method

A retrospective chart review of a patient diagnosed with post SARS-CoV-2 vaccination acute transverse myelitis, and a review of literature of all the reported cases of other post vaccination and transverse myelitis, from December 1st, 2010 till July 15th, 2021, was performed.

Conclusion

To our knowledge, this is the one of early reported case of transverse myelitis and with post SARS-CoV-2 vaccination, who responded well to plasmapheresis. Further studies would be recommended to identify the underlying correlation between COVID-19 vaccination and transverse myelitis.

中文翻译：

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SARS-CoV-2疫苗接种后的急性横贯性脊髓炎一例报告及文献复习

客观的

报告 COVID-19 疫苗接种后相关横贯性脊髓炎和异常 MRI 发现的独特病例和文献综述。

背景

据报道，冠状病毒病与多种神经系统表现有关，例如中风、格林-巴利综合征、脑膜脑炎等。仅有少数报道的新型冠状病毒 (n-CoV-2) 横贯性脊髓炎病例。在这里，我们确定了一名被诊断为急性横贯性脊髓炎的 COVID-19 疫苗接种后患者。

方法

对 2010 年 12 月 1 日至 2021 年 7 月 15 日诊断为 SARS-CoV-2 疫苗接种后急性横贯性脊髓炎患者的回顾性图表回顾，以及所有其他疫苗接种后和横贯性脊髓炎报告病例的文献回顾，是执行。

结论

据我们所知，这是一例早期报告的横贯性脊髓炎病例，在接种 SARS-CoV-2 疫苗后，对血浆置换术反应良好。建议进一步研究以确定 COVID-19 疫苗接种与横贯性脊髓炎之间的潜在相关性。