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Genomic insights into the origin, domestication and diversification of Brassica juncea
Nature Genetics ( IF 30.8 ) Pub Date : 2021-09-06 , DOI: 10.1038/s41588-021-00922-y
Lei Kang 1 , Lunwen Qian 1, 2 , Ming Zheng 3 , Liyang Chen 4 , Hao Chen 1 , Liu Yang 1 , Liang You 1 , Bin Yang 1, 5 , Mingli Yan 6 , Yuanguo Gu 7 , Tianyi Wang 4 , Sarah-Veronica Schiessl 8 , Hong An 9 , Paul Blischak 10 , Xianjun Liu 11 , Hongfeng Lu 4 , Dawei Zhang 6 , Yong Rao 5 , Donghai Jia 7 , Dinggang Zhou 6 , Huagui Xiao 5 , Yonggang Wang 7 , Xinghua Xiong 1 , Annaliese S Mason 8, 12 , J Chris Pires 9 , Rod J Snowdon 8 , Wei Hua 3 , Zhongsong Liu 1
Affiliation  

Despite early domestication around 3000 BC, the evolutionary history of the ancient allotetraploid species Brassica juncea (L.) Czern & Coss remains uncertain. Here, we report a chromosome-scale de novo assembly of a yellow-seeded B. juncea genome by integrating long-read and short-read sequencing, optical mapping and Hi-C technologies. Nuclear and organelle phylogenies of 480 accessions worldwide supported that B. juncea is most likely a single origin in West Asia, 8,000–14,000 years ago, via natural interspecific hybridization. Subsequently, new crop types evolved through spontaneous gene mutations and introgressions along three independent routes of eastward expansion. Selective sweeps, genome-wide trait associations and tissue-specific RNA-sequencing analysis shed light on the domestication history of flowering time and seed weight, and on human selection for morphological diversification in this versatile species. Our data provide a comprehensive insight into the origin and domestication and a foundation for genomics-based breeding of B. juncea.



中文翻译:

对芥菜起源、驯化和多样化的基因组学见解

尽管在公元前 3000 年左右进行了早期驯化,但古代异源四倍体Brassica juncea (L.) Czern & Coss 的进化历史仍不确定。在这里,我们通过整合长读长和短读长测序、光学作图和 Hi-C 技术,报告了黄种芥菜基因组的染色体规模从头组装。全球 480 个种质的核和细胞器系统发育支持B.juncea很可能是8,000-14,000年前通过自然种间杂交在西亚的单一起源。随后,新的作物类型通过自发的基因突变和基因渗入沿三个独立的东扩路线进化。选择性扫描、全基因组性状关联和组织特异性 RNA 测序分析揭示了开花时间和种子重量的驯化历史,以及人类选择这种多用途物种的形态多样化。我们的数据提供了对起源和驯化的全面了解,并为基于基因组学的芥菜育种奠定了基础。

更新日期:2021-09-06
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