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Correction to Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer’s Disease
Molecular Pharmaceutics ( IF 4.9 ) Pub Date : 2021-09-03 , DOI: 10.1021/acs.molpharmaceut.1c00661
Yijun Pan , Kotaro Omori , Izna Ali , Masanori Tachikawa , Tetsuya Terasaki , Kim L. R. Brouwer , Joseph A. Nicolazzo

Page 4078. In the original manuscript, we had incorrectly provided the values of the hepatocyte transporter and enzyme concentrations in Table 2. The protein concentrations for WT mice were reported under the APP/PS1 column, and the protein concentrations for APP/PS1 mice were reported under the WT column. This error does not impact on the ratio of Tg/WT values or the p values reported in Table 2 or the data presented in Figure 2, which are all correct in the original manuscript. Similarly, the text associated with the Results or Discussion is not impacted by this error. The new version of Table 2 is provided below. Indicates a significant difference in expression between WT and APP/PS1 mice (p < 0.05, n = 3). This article has not yet been cited by other publications.

中文翻译:

对家族性阿尔茨海默病小鼠模型中小肠药物转运蛋白和肝代谢酶表达改变的校正

第 4078 页。在原稿中,我们错误地提供了表 2 中肝细胞转运蛋白和酶浓度的值。WT 小鼠的蛋白质浓度报告在 APP/PS1 列下,APP/PS1 小鼠的蛋白质浓度为在 WT 栏下报告。此错误不会影响 Tg/WT 值的比率或表 2 中报告的p值或图 2 中提供的数据,这些在原稿中都是正确的。同样,与结果或讨论相关的文本不受此错误的影响。下面提供了表 2 的新版本。表明 WT 和 APP/PS1 小鼠之间的表达存在显着差异(p < 0.05,n= 3)。这篇文章还没有被其他出版物引用。
更新日期:2021-10-04
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