Infectious diseases are among the main causes of morbidity and mortality today. In facing this crisis, the development of new drug options and combat strategies is necessary. In this sense, drug repositioning or drug redirection has emerged for the faster identification of effective drugs. In this “Commentary,” the anti-infective properties of the class of proton pump inhibitors (PPIs) are emphasized. Studies report activities against bacterial, fungal, parasitic, and viral agents. In addition, we have provided in a table a summary of the specific characteristics of PPIs and some of their anti-infective activities.

中文翻译：

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质子泵抑制剂的抗感染特性：前景

传染病是当今发病率和死亡率的主要原因之一。面对这场危机，开发新的药物选择和作战策略是必要的。从这个意义上说，出现了药物重新定位或药物重定向以更快地识别有效药物。在这篇“评论”中，强调了质子泵抑制剂 (PPI) 类的抗感染特性。研究报告了对细菌、真菌、寄生虫和病毒病原体的活性。此外，我们在表格中汇总了 PPI 的具体特性及其一些抗感染活性。