当前位置: X-MOL 学术J. Inorg. Biochem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Recent advances in Cu(II)/Cu(I)-MOFs based nano-platforms for developing new nano-medicines
Journal of Inorganic Biochemistry ( IF 3.9 ) Pub Date : 2021-09-04 , DOI: 10.1016/j.jinorgbio.2021.111599
Yingman Sun 1 , Xiaodi Jiang 1 , Yiwei Liu 1 , Dong Liu 2 , Chen Chen 1 , Chengyu Lu 1 , Shuze Zhuang 3 , Abhinav Kumar 4 , Jianqiang Liu 1
Affiliation  

With increasing world population, life-span of humans and spread of viruses, myriad of diseases in human beings are becoming more and more common. Because of the interesting chemical and framework versatility and porosity of metal organic frameworks (MOFs) they find application in varied areas viz. catalysis, sensing, metal ion/gas storage, chemical separation, drug delivery, bio-imaging. This subclass of coordination polymers having interesting three-dimensional framework exhibits inordinate potential and hence may find application in treatment and cure of cancer, diabetes Alzheimer's and other diseases. The presented review focuses on the diverse mechanism of action, unique biological activity and advantages of copper-based metal organic framework (MOF) nanomaterials in medicine. Also, different methods used in the treatment of cancer and other diseases have been presented and the applications as well as efficacy of copper MOFs have been reviewed and discussed. Eventually, the current-status and potential of copper based MOFs in the field of anti-inflammatory, anti-bacterial and anti-cancer therapy as well as further investigations going on for this class of MOF-based multifunctional nanostructures in for developing new nano-medicines have been presented.



中文翻译:

基于 Cu(II)/Cu(I)-MOFs 的纳米平台用于开发新型纳米药物的最新进展

随着世界人口的增加,人类的寿命和病毒的传播,人类的各种疾病变得越来越普遍。由于金属有机骨架 (MOF) 有趣的化学和骨架多功能性和孔隙率,它们在不同的领域得到应用,即。催化、传感、金属离子/气体存储、化学分离、药物输送、生物成像。这种具有令人感兴趣的三维框架的配位聚合物亚类表现出极大的潜力,因此可能在癌症、糖尿病、阿尔茨海默氏症和其他疾病的治疗和治愈中得到应用。本综述重点介绍了铜基金属有机框架 (MOF) 纳米材料在医学中的多种作用机制、独特的生物活性和优势。此外,还介绍了用于治疗癌症和其他疾病的不同方法,并对铜 MOF 的应用和功效进行了回顾和讨论。最终,铜基 MOFs 在抗炎领域的现状和潜力,

更新日期:2021-09-08
down
wechat
bug