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Perspectives on gene copy number variation and pesticide resistance
Pest Management Science ( IF 4.1 ) Pub Date : 2021-09-04 , DOI: 10.1002/ps.6631
David G Heckel 1
Affiliation  

Although the generation of evolutionary diversity by gene duplication has long been known, the implications for pesticide resistance are just now beginning to be appreciated. A few examples will be cited to illustrate the point that there are many variations on the theme that gene duplication does not follow a set pattern. Transposable elements may facilitate the process but the mechanistic details are obscure and unpredictable. New developments in DNA sequencing technology and genome assembly promise to reveal more examples, yet care must be taken in interpreting the results of transcriptome and genome assemblies and independent means of validation are important. Once a specific gene family is identified, special methods generally must be used to avoid underestimating population polymorphisms and being trapped in preconceptions about the simplicity of the process. © 2021 The Author. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

中文翻译:

基因拷贝数变异和农药抗性的观点

尽管人们早就知道通过基因复制产生进化多样性,但现在才开始认识到其对农药抗性的影响。将引用一些例子来说明这一点,即基因复制不遵循固定模式这一主题有很多变化。可转座元素可能会促进该过程,但机械细节是模糊和不可预测的。DNA 测序技术和基因组组装的新发展有望揭示更多的例子,但在解释转录组和基因组组装的结果时必须小心,独立的验证方法很重要。一旦确定了特定的基因家族,通常必须使用特殊的方法来避免低估群体多态性和陷入对过程简单性的先入之见。© 2021 作者。John Wiley & Sons Ltd 代表化学工业协会出版的《害虫管理科学》。
更新日期:2021-09-04
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