The purpose is to describe a clinical case of orbital metastases as the presentation sign of the primary tumor, and the importance of a multidisciplinary diagnosis. A 70-year-old man attended the Ophthalmology Department referring ocular pain. Mild proptosis and a dermal lesion in the neck were noticed. Biopsy of the dermal lesion and systemic work-up were compatible with lung adenocarcinoma with metastatic dissemination. After one cycle of palliative chemotherapy, patient’s medical condition worsened, and he eventually died. Although rare, orbital symptoms can be the initial clinical presentation preceding the diagnosis of the primary silent lung neoplasm. Ophthalmologist has an important role in diagnoses of metastatic orbital cancer. Involvement of the multidisciplinary team is important for diagnosis and treatment.
Case Rep Ophthalmol 2021;12:729–733

中文翻译：

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眼球突出和皮肤病变是肺腺癌的表现体征

目的是将眼眶转移的临床病例描述为原发肿瘤的表现体征，以及多学科诊断的重要性。一名 70 岁男性因眼痛到眼科就诊。注意到轻度眼球突出和颈部皮肤病变。皮肤病变的活检和全身检查与转移性播散的肺腺癌相符。经过一个周期的姑息性化疗，患者病情恶化，最终死亡。虽然罕见，但眼眶症状可能是原发性无症状肺肿瘤诊断前的初始临床表现。眼科医生在转移性眼眶癌的诊断中具有重要作用。多学科团队的参与对于诊断和治疗很重要。
Case Rep Ophthalmol 2021；12:729–733