Objectives

This study aimed to prove the safety and efficacy of the contact aspiration using non-penetrating of thrombus (CANP) technique for the initial procedure for acute ischemic stroke and to increase operator familiarization with the technical aspects of the CANP technique.

Materials and Methods

A total of 103 patients with large-vessel stroke who were treated using thrombectomy alone at our institution between April 2019 and March 2021 were included in this study. CANP technique was performed using a large lumen catheter (inner diameter, ≥0.060 in.) without penetrating a thrombus. Results of the CANP technique, including the procedure time; first-pass effect (FPE); angiographical recanalization; functional independence; thrombus migration; and intracerebral hemorrhage (ICH) were compared with combined technique.

Results

A total of 77 patients (74.8%) were scheduled to undergo the CANP technique for initial procedure, and 50 (64.9%) attempted the CANP technique. Of 50 patients with CANP technique, 33 (66.0%) achieved angiographically good recanalization using CANP technique alone. FPE was achieved in 31 patients (62.0%) in CANP technique group; the rate of FPE was significantly higher (p = 0.008). Asymptomatic ICH were significantly smaller in the CANP technique group (p = 0.008). The median interval of only the CANP technique was 20 (IQR, 16–29.5) min for groin puncture to final recanalization, and was significantly faster (p < 0.001).

Conclusions

CANP technique was safe with low risk of hemorrhagic complication and effective for the initial procedure of acute ischemic stroke.

中文翻译：

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熟悉使用非穿透血栓 (CANP) 技术作为急性缺血性中风的初始程序的接触抽吸

目标

本研究旨在证明使用非穿透血栓 (CANP) 技术进行急性缺血性卒中初始手术的接触抽吸的安全性和有效性，并提高操作者对 CANP 技术技术方面的熟悉程度。

材料和方法

本研究共纳入 2019 年 4 月至 2021 年 3 月期间在我院仅接受血栓切除术治疗的 103 名大血管卒中患者。CANP 技术使用大管腔导管（内径，≥0.060 英寸）进行，没有穿透血栓。CANP技术的结果，包括手术时间；首过效应（FPE）；血管造影再通；功能独立；血栓迁移；和脑出血（ICH）与联合技术进行了比较。

结果

共有 77 名患者 (74.8%) 计划接受 CANP 技术进行初始手术，50 名患者 (64.9%) 尝试了 CANP 技术。在使用 CANP 技术的 50 名患者中，33 名 (66.0%) 仅使用 CANP 技术实现了血管造影良好的再通。CANP技术组31例患者（62.0%）实现了FPE；FPE 的发生率明显更高（p = 0.008）。CANP 技术组的无症状 ICH 显着减少 ( p = 0.008)。仅 CANP 技术的腹股沟穿刺到最终再通的中位间隔为 20（IQR，16-29.5）分钟，并且明显更快（p < 0.001）。

结论

CANP技术安全、出血并发症风险低，对急性缺血性卒中的初始手术有效。