The hydrogels are three-dimensional, water-swollen structures composed mainly of hydrophilic homo-polymers or copolymers utilized in various fields. This review explains in detail about the various methods used in the synthesis of hydrogel, their loading mechanism, their swelling index, their chemical and physical properties, and also comparative analysis between chemo-drug and drug-entrapped hydrogel. In this, we will also discuss various applications of hydrogel, which aid in treating diseases, like Alzheimer’s disease, Parkinson disease, etc., using modified drug delivery mechanism. Though these diseases have various methods of treatment, they have a common ground and that is the need for definite amounts and a prolonged release of drugs which will be possible with the aid of hydrogels. The use of hydrogel is believed to be an upgrade in the medical field, and its involvement in treatments is considered to be sincerely encouraged.

水凝胶是主要由亲水性均聚物或共聚物组成的三维、水溶胀结构，用于各个领域。这篇综述详细解释了用于合成水凝胶的各种方法、它们的负载机制、它们的溶胀指数、它们的化学和物理特性，以及化学药物和药物包埋水凝胶之间的比较分析。在此，我们还将讨论水凝胶的各种应用，它们使用改良的药物递送机制帮助治疗阿尔茨海默病、帕金森病等疾病。尽管这些疾病有多种治疗方法，但它们有一个共同点，那就是需要确定数量的药物并延长释放时间，而这在水凝胶的帮助下是可能的。