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COVID-19 and Cancer: A Review of the Registry-Based Pandemic Response.
JAMA Oncology ( IF 28.4 ) Pub Date : 2021-12-01 , DOI: 10.1001/jamaoncol.2021.4083
Aakash Desai 1, 2 , Turab J Mohammed 3 , Narjust Duma 4 , Marina C Garassino 5 , Lisa K Hicks 6 , Nicole M Kuderer 7 , Gary H Lyman 8, 9, 10 , Sanjay Mishra 11 , David J Pinato 12, 13 , Brian I Rini 11 , Solange Peters 14 , Jeremy L Warner 11 , Jennifer G Whisenant 11 , William A Wood 15 , Michael A Thompson 16
Affiliation  

Importance The COVID-19 pandemic has had consequences for patients with cancer worldwide and has been associated with delays in diagnosis, interruption of treatment and follow-up care, and increases in overall infection rates and premature mortality. Observations Despite the challenges experienced during the pandemic, the global oncology community has responded with an unprecedented level of investigation, collaboration, and technological innovation through the rapid development of COVID-19 registries that have allowed an increased understanding of the natural history, risk factors, and outcomes of patients with cancer who are diagnosed with COVID-19. This review describes 14 major registries comprising more than 28 500 patients with cancer and COVID-19; these ongoing registry efforts have provided an improved understanding of the impact and outcomes of COVID-19 among patients with cancer. Conclusions and Relevance An initiative is needed to promote active collaboration between different registries to improve the quality and consistency of information. Well-designed prospective and randomized clinical trials are needed to collect high-level evidence to guide long-term epidemiologic, behavioral, and clinical decision-making for this and future pandemics.

中文翻译:

COVID-19 和癌症:基于登记的流行病应对措施回顾。

重要性 COVID-19 大流行对全世界癌症患者造成了影响,并与诊断延迟、治疗和后续护理中断以及总体感染率和过早死亡率增加有关。观察 尽管在大流行期间经历了挑战,但全球肿瘤学界通过 COVID-19 登记的快速发展,以前所未有的调查、合作和技术创新水平做出了反应,这使人们能够更好地了解自然史、风险因素、以及被诊断患有 COVID-19 的癌症患者的结果。这篇综述描述了 14 个主要登记处,包括超过 28,500 名癌症和 COVID-19 患者;这些正在进行的登记工作使人们更好地了解了 COVID-19 对癌症患者的影响和结果。结论和相关性 需要采取一项举措来促进不同注册管理机构之间的积极合作,以提高信息的质量和一致性。需要精心设计的前瞻性和随机临床试验来收集高水平证据,以指导针对此次和未来大流行的长期流行病学、行为和临床决策。
更新日期:2021-09-02
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