Molecular exchange dynamics between spherical complex coacervate core micelles (C3Ms) are documented using time-resolved small-angle neutron scattering measurements (TR-SANS), and the effects of salt concentration, type of charges, and core block polydispersity to the chain exchange are quantified. Isotopically labeled block copolyelectrolytes were prepared by postpolymerization modification of two nearly identical poly(ethylene oxide-b-allyl glycidyl ether), one with normal and the other with deuterated PEO blocks (i.e., hPEO–PAGE and dPEO–PAGE). The observed rates at multiple salt concentrations are consolidated using time-salt superposition shift factors representing chain exchange rates and analyzed. Our comprehensive analytical relaxation function based on the sticky-Rouse model and the thermodynamic barrier for core block extraction successfully describes the molecular exchange kinetics between the isotopically labeled C3Ms. We believe this work provides fundamental design criteria for C3Ms with engineered chain exchange dynamics.

中文翻译：

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复杂凝聚核心胶束中的分子交换动力学：缔合相互作用的作用

使用时间分辨小角中子散射测量 (TR-SANS) 记录了球形复合凝聚核心胶束 (C3Ms) 之间的分子交换动力学，并且盐浓度、电荷类型和核心嵌段多分散性对链交换的影响是量化的。同位素标记的嵌段共聚电解质是通过对两种几乎相同的聚（环氧乙烷-b-烯丙基缩水甘油醚），一种是正常的，另一种是氘化的 PEO 嵌段（即 hPEO-PAGE 和 dPEO-PAGE）。使用代表链交换率的时间盐叠加移位因子合并并分析在多个盐浓度下观察到的速率。我们基于 Sticky-Rouse 模型和核心块提取热力学势垒的综合分析弛豫函数成功地描述了同位素标记的 C3M 之间的分子交换动力学。我们相信这项工作为具有工程链交换动力学的 C3M 提供了基本的设计标准。