Anxiety disorders are common in adolescence but outcomes for adolescents are unclear and we do not know what factors moderate treatment outcome for this age group. We conducted meta-analyses to establish the effectiveness of psychological therapies for adolescent anxiety disorders in (i) reducing anxiety disorder symptoms, and (ii) remission from the primary anxiety disorder, compared with controls, and examine potential moderators of treatment effects. The protocol was registered with PROSPERO (CRD42018091744). Electronic databases (Web of Science, MEDLINE, Psycinfo, EMBASE) were searched from January 1990 to December 2019. 2511 articles were reviewed, those meeting strict criteria were included. Random effects meta-analyses were conducted. Analyses of symptom severity outcomes comprised sixteen studies (CBT k = 15, non-CBT k = 1; n = 766 adolescents), and analyses of diagnostic remission outcomes comprised nine (CBT k = 9; n = 563 adolescents). Post-treatment, those receiving treatment were significantly more likely to experience reduced symptom severity (SMD = 0.454, 95% CI 0.22–0.69) and remission from the primary anxiety disorder than controls (RR = 7.94, 95% CI 3.19–12.7) (36% treatment vs. 9% controls in remission). None of the moderators analysed were statistically significant. Psychological therapies targeting anxiety disorders in adolescents are more effective than controls. However, with only just over a third in remission post-treatment, there is a clear need to develop more effective treatments for adolescents, evaluated through high-quality randomised controlled trials incorporating active controls and follow-up data.

焦虑症在青春期很常见，但青少年的结果尚不清楚，我们不知道哪些因素会影响该年龄组的治疗结果。我们进行了荟萃分析，以确定与对照组相比，青少年焦虑症的心理疗法在 (i) 减少焦虑症症状和 (ii) 原发性焦虑症缓解方面的有效性，并检查治疗效果的潜在调节因素。该协议已向 PROSPERO (CRD42018091744) 注册。检索了 1990 年 1 月至 2019 年 12 月的电子数据库（Web of Science、MEDLINE、Psycinfo、EMBASE）。审查了 2511 篇文章，纳入了符合严格标准的文章。进行了随机效应荟萃分析。对症状严重程度结果的分析包括 16 项研究（CBT k = 15，非 CBT k = 1；n  = 766 名青少年），对诊断缓解结果的分析包括 9 个（CBT k = 9；n = 563 名青少年）。治疗后，与对照组相比，接受治疗的患者症状严重程度降低（SMD = 0.454, 95% CI 0.22-0.69）和原发性焦虑症缓解的可能性显着增加（RR = 7.94, 95% CI 3.19-12.7）（ 36% 的治疗与 9% 的控制缓解）。所分析的主持人均无统计学意义。针对青少年焦虑症的心理治疗比对照组更有效。然而，只有超过三分之一的治疗后缓解，显然需要为青少年开发更有效的治疗方法，并通过纳入主动对照和随访数据的高质量随机对照试验进行评估。