An efficient protocol for enantioselective domino Michael/α-alkylation between α,β-unsaturated aldehydes and non-stabilized nitro alkyl halides has been reported. Reaction catalyzed by chiral secondary amines as organocatalysts gives an access to enantiomerically enriched 1,2,3-trisubstituted cyclopentanes with wide range of substitution.

中文翻译：

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1,2,3-三取代环戊烷的对映选择性有机催化合成

α,β-不饱和醛和非稳定硝基烷基卤化物之间的对映选择性多米诺迈克尔/α-烷基化的有效方案已被报道。手性仲胺作为有机催化剂催化的反应提供了对映异构富集的具有广泛取代范围的 1,2,3-三取代环戊烷。