Introduction:

The present study aimed to evaluate the feasibility and efficacy of CogmedRM, a computerized, home-based working memory (WM) training program, in children with NF1.

Method:

A pre-post design was used to evaluate changes in performance-based measures of attention and WM, and parent-completed ratings of executive functioning. Children meeting eligibility criteria completed CogmedRM over 9 weeks. Primary outcomes included compliance statistics and change in attention and WM scores.

Results:

Thirty-one children (52% male; M age = 10.97 ± 2.51), aged 8-15, were screened for participation; 27 children (87%) evidenced WM difficulties and participated in CogmedRM training. On average, participants completed 19.7 out of 25 prescribed sessions, with an adherence rate of 69%. Participants demonstrated improvements in short-term memory, attention, and executive functioning (all Ps < .05).

Conclusion:

Results suggest that computerized, home-based WM training programs may be both feasible and efficacious for children with NF1 and cognitive deficits.

中文翻译：

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1 型神经纤维瘤病 (NF1) 儿童的计算机化工作记忆训练：一项试点研究

介绍：

本研究旨在评估CogmedRM（一种计算机化的、基于家庭的工作记忆 (WM) 培训计划）在 NF1 儿童中的可行性和有效性。

方法：

使用前后设计来评估基于绩效的注意力和 WM 测量的变化，以及父母完成的执行功能评级。符合资格标准的儿童在 9 周内完成了CogmedRM 。主要结果包括依从性统计数据以及注意力和 WM 分数的变化。

结果：

对 31 名 8-15 岁的儿童（52% 男性；M 年龄 = 10.97 ± 2.51）进行了参与筛查；27 名儿童 (87%) 证明了 WM 困难并参加了CogmedRM培训。平均而言，参与者完成了 25 个规定会话中的 19.7 个，依从率为 69%。参与者表现出短期记忆、注意力和执行功能的改善（所有Ps < .05）。

结论：

结果表明，计算机化的、以家庭为基础的 WM 培训计划对于患有 NF1 和认知缺陷的儿童可能既可行又有效。