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Potential use of bile salts in lipid self-assembled systems for the delivery of phytochemicals
Current Opinion in Colloid & Interface Science ( IF 8.9 ) Pub Date : 2021-09-02 , DOI: 10.1016/j.cocis.2021.101502
Aygul Can 1 , Arwen I.I. Tyler 1 , Alan R. Mackie 1
Affiliation  

Phytochemicals show many desirable functions such as anti-oxidant, anti-microbial, anti-inflammatory, anti-carcinogenic, anti-ageing, activities and so on.These biological functions can only be seen when the compounds are delivered at sufficient concentrations. However, the bioavailability of phytonutrients suffers from their limited absorption, transformation, and rapid clearance from the circulation. In this review, we survey recent studies on the use of bile salts in lipid self-assembled systems to enhance the bioavailability of phytochemicals and, consequently, their biological activity. The effect of bile salts on lipid self-assembled systems in terms of morphology, encapsulation efficiency, stability, bioavailability, and biological activities are discussed.



中文翻译:

胆汁盐在脂质自组装系统中用于输送植物化学物质的潜在用途

植物化学物质显示出许多理想的功能,如抗氧化、抗微生物、抗炎、抗癌、抗衰老、活性等。这些生物功能只有在化合物以足够的浓度递送时才能显现。然而,植物营养素的生物利用度受到它们有限的吸收、转化和从循环中快速清除的影响。在这篇综述中,我们调查了最近关于在脂质自组装系统中使用胆汁盐来提高植物化学物质的生物利用度及其生物活性的研究。讨论了胆汁盐对脂质自组装系统在形态、封装效率、稳定性、生物利用度和生物活性方面的影响。

更新日期:2021-10-06
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