当前位置：
X-MOL 学术
›
Neurol. India
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Objective Evaluation of Cerebral Venous Sinus Attenuation on Plain CT Brain and Detecting Anemia. Noticing the “Unnoticed”
Neurology India ( IF 2.7 ) Pub Date : 2021-07-01 , DOI: 10.4103/0028-3886.323896 Poornima Digge 1 , Viral Patel 1 , K V Bharath 1 , Koteshwar K Prakashini 2 , Karamchand H Patil 3
Context: Plain computed tomography (CT) of the brain is an important first-line investigation of choice in an acute neurologic setup. Unless clinically suspected concealed areas like the confluence of venous sinuses often go unnoticed. Diagnosing anemia, thrombosis, or polycythemia correlating the CT attenuation values might prove to be fruitful in early patient management where the mode of varied clinical presentations causes a clinical dilemma.
Aims: 1) To determine the objective correlation between CT attenuation of the cerebral venous sinus and hemoglobin (Hb) as well as hematocrit (HCT) value and 2) to detect anemia from measuring venous sinus attenuation.
Methods and Materials: An exploratory study design of 200 patients, who had plain CT of the head and Hb and HCT levels obtained within 24 h of the scan.
Statistical Analysis Used: Two-tailed unpaired t-test was used to test the difference between two independent samples. Correlation and regression analyses were used to assess the correlation between two quantitative variables.
Results: A significant correlation was observed between the Hb-Hounsfield unit (HU) and HCT-HU. The simple linear regression model revealed that HU (P value < 0.001) was significantly correlated with Hb and the regression model was, Hb = 2.1 + 0.2 × HU. Similarly, HU (P value < 0.001) was significantly correlated with HCT and regression model was HCT = 6.2 + 0.7 × HU.
Conclusions: Objective attenuation values of dural sinuses on plain CT can be positively correlated with Hb and HCT values. Considering the cutoff of 35.5 HU, we were able to show the specificity of 100% for the detection of anemia.
中文翻译：
对普通CT脑部脑静脉窦衰减的客观评价及贫血的检测。注意到“不被注意”
背景：大脑的普通计算机断层扫描 (CT) 是急性神经系统设置中选择的重要一线检查。除非临床怀疑像静脉窦汇合处这样的隐蔽区域，否则通常会被忽视。诊断与 CT 衰减值相关的贫血、血栓形成或红细胞增多症可能证明在早期患者管理中是富有成效的，因为各种临床表现的模式会导致临床困境。
目的： 1）确定脑静脉窦CT衰减与血红蛋白（Hb）以及红细胞比容（HCT）值之间的客观相关性和2）通过测量静脉窦衰减来检测贫血。
方法和材料：一项对 200 名患者进行的探索性研究设计，这些患者在扫描后 24 小时内进行了头部 CT 平扫以及 Hb 和 HCT 水平。
使用的统计分析：双尾非配对t检验用于测试两个独立样本之间的差异。相关和回归分析用于评估两个定量变量之间的相关性。
结果：在 Hb-Hounsfield 单位 (HU) 和 HCT-HU 之间观察到显着相关性。简单线性回归模型显示HU（P值<0.001）与Hb显着相关，回归模型为Hb=2.1+0.2×HU。同样，HU ( Pvalue < 0.001) 与 HCT 显着相关，回归模型为 HCT = 6.2 + 0.7 × HU。
结论： CT平扫硬脑膜窦客观衰减值与Hb、HCT值呈正相关。考虑到 35.5 HU 的截止值，我们能够显示 100% 的特异性检测贫血。
更新日期：2021-09-02
Neurology India ( IF 2.7 ) Pub Date : 2021-07-01 , DOI: 10.4103/0028-3886.323896 Poornima Digge 1 , Viral Patel 1 , K V Bharath 1 , Koteshwar K Prakashini 2 , Karamchand H Patil 3
Affiliation
Context: Plain computed tomography (CT) of the brain is an important first-line investigation of choice in an acute neurologic setup. Unless clinically suspected concealed areas like the confluence of venous sinuses often go unnoticed. Diagnosing anemia, thrombosis, or polycythemia correlating the CT attenuation values might prove to be fruitful in early patient management where the mode of varied clinical presentations causes a clinical dilemma.
Aims: 1) To determine the objective correlation between CT attenuation of the cerebral venous sinus and hemoglobin (Hb) as well as hematocrit (HCT) value and 2) to detect anemia from measuring venous sinus attenuation.
Methods and Materials: An exploratory study design of 200 patients, who had plain CT of the head and Hb and HCT levels obtained within 24 h of the scan.
Statistical Analysis Used: Two-tailed unpaired t-test was used to test the difference between two independent samples. Correlation and regression analyses were used to assess the correlation between two quantitative variables.
Results: A significant correlation was observed between the Hb-Hounsfield unit (HU) and HCT-HU. The simple linear regression model revealed that HU (P value < 0.001) was significantly correlated with Hb and the regression model was, Hb = 2.1 + 0.2 × HU. Similarly, HU (P value < 0.001) was significantly correlated with HCT and regression model was HCT = 6.2 + 0.7 × HU.
Conclusions: Objective attenuation values of dural sinuses on plain CT can be positively correlated with Hb and HCT values. Considering the cutoff of 35.5 HU, we were able to show the specificity of 100% for the detection of anemia.
中文翻译：
对普通CT脑部脑静脉窦衰减的客观评价及贫血的检测。注意到“不被注意”
背景：大脑的普通计算机断层扫描 (CT) 是急性神经系统设置中选择的重要一线检查。除非临床怀疑像静脉窦汇合处这样的隐蔽区域，否则通常会被忽视。诊断与 CT 衰减值相关的贫血、血栓形成或红细胞增多症可能证明在早期患者管理中是富有成效的，因为各种临床表现的模式会导致临床困境。
目的： 1）确定脑静脉窦CT衰减与血红蛋白（Hb）以及红细胞比容（HCT）值之间的客观相关性和2）通过测量静脉窦衰减来检测贫血。
方法和材料：一项对 200 名患者进行的探索性研究设计，这些患者在扫描后 24 小时内进行了头部 CT 平扫以及 Hb 和 HCT 水平。
使用的统计分析：双尾非配对t检验用于测试两个独立样本之间的差异。相关和回归分析用于评估两个定量变量之间的相关性。
结果：在 Hb-Hounsfield 单位 (HU) 和 HCT-HU 之间观察到显着相关性。简单线性回归模型显示HU（P值<0.001）与Hb显着相关，回归模型为Hb=2.1+0.2×HU。同样，HU ( Pvalue < 0.001) 与 HCT 显着相关，回归模型为 HCT = 6.2 + 0.7 × HU。
结论： CT平扫硬脑膜窦客观衰减值与Hb、HCT值呈正相关。考虑到 35.5 HU 的截止值，我们能够显示 100% 的特异性检测贫血。
京公网安备 11010802027423号