Type 2 diabetes mellitus (T2DM) impairs bone strength and is a significant risk factor for hip fracture, yet currently there is no reliable tool to assess this risk. Most risk stratification methods rely on bone mineral density, which is not impaired by diabetes, rendering current tests ineffective. CT-based finite element analysis (CTFEA) calculates the mechanical response of bone to load and uses the yield strain, which is reduced in T2DM patients, to measure bone strength. The purpose of this feasibility study was to examine whether CTFEA could be used to assess the hip fracture risk for T2DM patients.

中文翻译：

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使用基于 CT 的自主有限元方法评估 2 型糖尿病患者的髋部骨折风险：可行性研究。

2 型糖尿病 (T2DM) 会损害骨强度，是髋部骨折的重要危险因素，但目前还没有可靠的工具来评估这种风险。大多数风险分层方法依赖于不受糖尿病影响的骨矿物质密度，这使得当前的测试无效。基于 CT 的有限元分析 (CTFEA) 计算骨骼对负载的机械响应，并使用在 T2DM 患者中降低的屈服应变来测量骨骼强度。本可行性研究的目的是检验 CTFEA 是否可用于评估 T2DM 患者的髋部骨折风险。