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Vinyl sulfone synthesis via copper-catalyzed three-component decarboxylative addition
Organic & Biomolecular Chemistry ( IF 3.2 ) Pub Date : 2021-08-26 , DOI: 10.1039/d1ob01435h
Seunghwan An 1 , Kwang Ho Song 2 , Sunwoo Lee 1
Affiliation  

The synthesis of vinyl sulfone derivatives via the reaction of arylpropiolic acids, K2S2O5, and aryl boronic acids is reported. The CuBr2/1,10-phenanthroline catalytic system in the presence of acetic acid provides the desired vinyl sulfones in moderate to good yield. Furthermore, the methodology features excellent functional group tolerance.

中文翻译:

铜催化三组分脱羧加成合成乙烯基砜

报道了通过芳基丙炔酸、K 2 S 2 O 5和芳基硼酸反应合成乙烯基砜衍生物。在乙酸存在下的 CuBr 2 /1,10-菲咯啉催化体系以中等至良好的产率提供所需的乙烯基砜。此外,该方法具有出色的官能团耐受性。
更新日期:2021-09-01
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