The multicomponent reaction (MCR) strategy for the construction of important molecular scaffolds is in trending nowadays and among them, A³-coupling stands in a significant position. Aldehyde, amine and alkynes are coupled in this particular reaction via C-H activation process. Herein, we have reported zinc ferrite nanoparticles as magnetically separable heterogeneous catalyst for A³-coupling reaction with attractive attributes like excellent productivity, selectivity and better reusability. Moreover, the catalyst can also be effectively applied for the synthesis of various NH-triazoles with quantitative yields of the products. A plausible mechanism has been proposed for the synthesis of NH-triazoles followed by validation with computational study.

构建重要分子支架的多组分反应（MCR）策略是当今的趋势，其中A ^{3 -}偶联处于重要地位。醛、胺和炔烃通过 CH 活化过程在该特定反应中偶联。在此，我们报道了铁酸锌纳米颗粒作为 A ³偶联反应的可磁分离多相催化剂，具有出色的生产率、选择性和更好的可重复使用性等吸引人的属性。此外，该催化剂还可以有效地应用于各种NH-三唑类化合物的合成，产品的收率很高。已经提出了合成 NH-三唑的合理机制，然后通过计算研究进行验证。