In this study, characterization and antiinflammatory activity of Undaria pinnatifida root (UPR) water extracts treated by gamma (γ)-irradiation were investigated. The UPR powder was dissolved in distilled water to form UPR water extracts. Subsequently, they were irradiated with cobalt-60 γ-rays in a dose range from 3 to 20 kGy. In the reducing sugar and viscosity analyses, the reducing sugar content showed a two-fold increase at 20 kGy compared to the non-irradiated control, and UPR water extracts viscosity decreased with increasing irradiation dose. Using thin layer chromatography (TLC), UPR polysaccharides were degraded to monosaccharides after γ-irradiation treatment. Moreover, UPR water extracts treated with γ-irradiation inhibited the production of nitric oxide (NO) and pro-inflammatory cytokine (IL-6 and TNF-α) activity. Therefore, γ-irradiation not only degrades UPR water extracts polysaccharides, but also increases the anti-inflammatory activity of UPR water extracts.

在这项研究中，裙带菜的特性和抗炎活性研究了经伽马 (γ) 辐射处理的根 (UPR) 水提取物。将 UPR 粉末溶解在蒸馏水中以形成 UPR 水提取物。随后，他们接受剂量范围为 3 至 20 kGy 的钴 60 γ 射线照射。在还原糖和粘度分析中，还原糖含量在 20 kGy 时比未照射的对照增加了两倍，UPR 水提取物的粘度随着照射剂量的增加而降低。使用薄层色谱 (TLC)，UPR 多糖在 γ 辐射处理后降解为单糖。此外，用γ-辐射处理的UPR水提取物抑制一氧化氮（NO）和促炎细胞因子（IL-6和TNF-α）活性的产生。因此，γ-辐照不仅降解UPR水提取物多糖，