Modification of the recently reported ¹⁹F-detected 1,1-ADEQUATE experiment that incorporates dual-optimization to selectively invert a wide range of ¹J_CC correlations in a 1,n-ADEQUATE experiment is reported. Parameters for the dual-optimization segment of the pulse sequence were modified to accommodate the increased size of ¹J_CC homonuclear coupling constants of poly- and perfluorinated molecules relative to protonated molecules to allow broadband inversion of the ¹J_CC correlations. The observation and utility of isotope shifts are reported for the first time for 1,1- and 1,n-ADEQUATE correlations.

中文翻译：

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19F-检测双优化倒置 1JCC 1,n-ADEQUATE

报告了对最近报道的¹⁹ F 检测到的 1,1-ADEQUATE 实验的修改，该实验结合了双重优化，以在 1,n-ADEQUATE 实验中选择性地反转广泛的¹ J _{CC相关性。}修改了脉冲序列的双重优化部分的参数，以适应多氟化和全氟化分子相对于质子化分子的¹ J _{CC同核耦合常数的增加，以允许}¹ J _CC相关性的宽带反转。对于 1,1- 和 1,n-ADEQUATE 相关性，首次报道了同位素位移的观察和效用。