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A Method for Manufacturing Flexible Microfluidic Chip Based on Soluble Material
Journal of Nanomaterials ( IF 3.791 ) Pub Date : 2021-09-01 , DOI: 10.1155/2021/1280338 Junyao Wang 1 , Xingyu Chen 1 , Huan Liu 1 , Gongchen Sun 1 , Yunpeng Li 1 , Tianhong Lang 1 , Rui Wang 1 , Bowen Cui 1
Journal of Nanomaterials ( IF 3.791 ) Pub Date : 2021-09-01 , DOI: 10.1155/2021/1280338 Junyao Wang 1 , Xingyu Chen 1 , Huan Liu 1 , Gongchen Sun 1 , Yunpeng Li 1 , Tianhong Lang 1 , Rui Wang 1 , Bowen Cui 1
Affiliation
In this paper, a novel method for manufacturing flexible microfluidic chips without bonding process is proposed, which combines 3D printing technology and material dissolution technology. The manufacturing process of the microfluidic chip is as follows: a soluble HIPS mold with a preset shape is manufactured by 3D printing and placed in a molten PDMS solution for solidification. Soak in the limonene material to dissolve the mold and form a microchannel in the cured PDMS. Experimental studies have shown that the temperature and concentration of the limonene solution have an important effect on the dissolution rate. A 0.62 cm3 HIPS mold has the fastest dissolution rate at 100°C and 50% concentration. The proposed method provided a new idea for fabricating flexible microfluidic chip. Compared to bonding process, it has the characteristics of not relying on complicated processing conditions and low manufacturing cost.
中文翻译:
一种基于可溶性材料的柔性微流控芯片制造方法
本文提出了一种无需键合工艺的柔性微流控芯片制造新方法,将3D打印技术与材料溶解技术相结合。微流控芯片的制造过程如下:通过3D打印制造出具有预设形状的可溶性HIPS模具,置于熔融的PDMS溶液中固化。浸泡在柠檬烯材料中以溶解模具并在固化的 PDMS 中形成微通道。实验研究表明,柠檬烯溶液的温度和浓度对溶解速率有重要影响。一个 0.62 厘米3HIPS 模具在 100°C 和 50% 浓度下的溶解速度最快。该方法为柔性微流控芯片的制备提供了新思路。与键合工艺相比,它具有不依赖复杂的加工条件和制造成本低的特点。
更新日期:2021-09-01
中文翻译:
一种基于可溶性材料的柔性微流控芯片制造方法
本文提出了一种无需键合工艺的柔性微流控芯片制造新方法,将3D打印技术与材料溶解技术相结合。微流控芯片的制造过程如下:通过3D打印制造出具有预设形状的可溶性HIPS模具,置于熔融的PDMS溶液中固化。浸泡在柠檬烯材料中以溶解模具并在固化的 PDMS 中形成微通道。实验研究表明,柠檬烯溶液的温度和浓度对溶解速率有重要影响。一个 0.62 厘米3HIPS 模具在 100°C 和 50% 浓度下的溶解速度最快。该方法为柔性微流控芯片的制备提供了新思路。与键合工艺相比,它具有不依赖复杂的加工条件和制造成本低的特点。