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SARS-CoV-2 screening testing in schools for children with intellectual and developmental disabilities
Journal of Neurodevelopmental Disorders ( IF 4.9 ) Pub Date : 2021-09-01 , DOI: 10.1186/s11689-021-09376-z
Michael R Sherby 1 , Tyler J Walsh 2 , Albert M Lai 3 , Julie A Neidich 4 , Joyce E Balls-Berry 5 , Stephanie M Morris 1 , Richard Head 6 , Christopher G Prener 7 , Jason G Newland 2 , Christina A Gurnett 1 ,
Affiliation  

Transmission of SARS-CoV-2 in schools primarily for typically developing children is rare. However, less is known about transmission in schools for children with intellectual and developmental disabilities (IDD), who are often unable to mask or maintain social distancing. The objectives of this study were to determine SARS-CoV-2 positivity and in-school transmission rates using weekly screening tests for school staff and students and describe the concurrent deployment of mitigation strategies in six schools for children with IDD. From November 23, 2020, to May, 28, 2021, weekly voluntary screening for SARS-CoV-2 with a high sensitivity molecular-based saliva test was offered to school staff and students. Weekly positivity rates were determined and compared to local healthcare system and undergraduate student screening data. School-based transmission was assessed among participants quarantined for in-school exposure. School administrators completed a standardized survey to assess school mitigation strategies. A total of 59 students and 416 staff participated. An average of 304 school staff and students were tested per week. Of 7289 tests performed, 21 (0.29%) new SARS-CoV-2 positive cases were identified. The highest weekly positivity rate was 1.2% (n = 4) across all schools, which was less than community positivity rates. Two cases of in-school transmission were identified, each among staff, representing 2% (2/103) of participants quarantined for in-school exposure. Mitigation strategies included higher than expected student mask compliance, reduced room capacity, and phased reopening. During 24 weeks that included the peak of the COVID-19 pandemic in winter 2020-21, we found lower rates of SARS-CoV-2 screening test positivity among staff and students of six schools for children with IDD compared to community rates. In-school transmission of SARS-CoV-2 was low among those quarantined for in-school exposure. However, the impact of the emerging SARS-CoV-2 Delta variant on the effectiveness of these proven mitigation strategies remains unknown. Prior to enrollment, this study was registered at ClinicalTrials.gov on September 25, 2020, identifier NCT04565509 , titled Supporting the Health and Well-being of Children with Intellectual and Developmental Disability During COVID-19 Pandemic.

中文翻译:

在学校为智力和发育障碍儿童进行 SARS-CoV-2 筛查测试

SARS-CoV-2 在主要针对发育正常的儿童的学校中传播的情况很少见。然而,对于智力和发育障碍 (IDD) 儿童在学校中的传播知之甚少,他们通常无法掩饰或保持社交距离。本研究的目的是通过每周对学校教职员工和学生进行的筛查测试来确定 SARS-CoV-2 阳性和校内传播率,并描述在六所学校为 IDD 儿童同时部署的缓解策略。从 2020 年 11 月 23 日到 2021 年 5 月 28 日,每周向学校教职员工和学生提供通过高灵敏度分子唾液测试自愿筛查 SARS-CoV-2。确定每周阳性率,并与当地医疗保健系统和本科生筛查数据进行比较。在因校内暴露而被隔离的参与者中评估了基于学校的传播。学校管理人员完成了一项标准化调查,以评估学校缓解策略。共有59名学生和416名教职员工参加。每周平均有 304 名学校教职员工和学生接受测试。在进行的 7289 次检测中,发现了 21 例(0.29%)新的 SARS-CoV-2 阳性病例。所有学校的最高每周阳性率为 1.2%(n = 4),低于社区阳性率。确定了两例校内传播病例,每例都发生在工作人员中,占因校内暴露而被隔离的参与者的 2% (2/103)。缓解策略包括高于预期的学生口罩合规性、减少房间容量和分阶段重新开放。在包括 2020-21 年冬季 COVID-19 大流行高峰在内的 24 周内,我们发现,与社区比率相比,六所学校的 IDD 儿童学校的教职工和学生的 SARS-CoV-2 筛查阳性率较低。在因校内接触而被隔离的人中,SARS-CoV-2 的校内传播率较低。然而,新出现的 SARS-CoV-2 Delta 变体对这些经过验证的缓解策略的有效性的影响仍然未知。入组前,该研究已于 2020 年 9 月 25 日在 ClinicalTrials.gov 注册,标识符为 NCT04565509,标题为在 COVID-19 大流行期间支持智力和发育障碍儿童的健康和福祉。在因校内接触而被隔离的人中,SARS-CoV-2 的校内传播率较低。然而,新出现的 SARS-CoV-2 Delta 变体对这些经过验证的缓解策略的有效性的影响仍然未知。入组前,该研究已于 2020 年 9 月 25 日在 ClinicalTrials.gov 注册,标识符为 NCT04565509,标题为在 COVID-19 大流行期间支持智力和发育障碍儿童的健康和福祉。在因校内接触而被隔离的人中,SARS-CoV-2 的校内传播率较低。然而,新出现的 SARS-CoV-2 Delta 变体对这些经过验证的缓解策略的有效性的影响仍然未知。入组前,该研究已于 2020 年 9 月 25 日在 ClinicalTrials.gov 注册,标识符为 NCT04565509,标题为在 COVID-19 大流行期间支持智力和发育障碍儿童的健康和福祉。
更新日期:2021-09-01
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