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Papulo-purpuric dermatitis of childhood: a distinct PLEVA-like eruption associated to SARS-CoV-2 infection. Clinical, histopathological and immunohistochemical study of 10 cases
Pediatric Dermatology ( IF 1.5 ) Pub Date : 2021-08-31 , DOI: 10.1111/pde.14777
Raffaele Gianotti 1 , Lucia Restano 2 , Mario Cutrone 3 , Cristiana Colonna 2 , Giovanni Fellegara 4 , Isacco Debernardi 4 , Francesca Boggio 5 , Alessandro Del Gobbo 5 , Nicola Adriano Monzani 6 , Claudio Tripodo 7 , Carlo Gelmetti 2 , Emilio Berti 1
Affiliation  

We observed ten children with a papular eruption with purpuric features during the SARS-CoV-2 pandemic in Northern Italy (May-December 2020). Histological examination showed signs of SARS-CoV-2-related dermatosis. Evidence of nucleocapsid viral proteins using SARS-CoV-2 (2019-nCoV) nucleocapsid antibody revealed cuticular staining of the deep portion of the eccrine glands in all cases.

中文翻译:

儿童丘疹紫癜性皮炎:与 SARS-CoV-2 感染相关的独特 PLEVA 样皮疹。10例临床、组织病理及免疫组化研究

在意大利北部的 SARS-CoV-2 大流行期间(2020 年 5 月至 12 月),我们观察到 10 名出现具有紫癜特征的丘疹性皮疹的儿童。组织学检查显示 SARS-CoV-2 相关皮肤病的迹象。使用 SARS-CoV-2(2019-nCoV)核衣壳抗体的核衣壳病毒蛋白的证据显示,在所有情况下,外分泌腺深部的表皮染色。
更新日期:2021-11-09
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