On the basis of the electromediated regeneration of beta-nicotinamide adenine dinucleotide hydrate (NADH) by chloro(2,2′-bipyridyl) (pentamethylcyclopentadienyl)-rhodium (III) chloride complex – Rh(III), the manuscript describes a modelling approach inspired by multiphase chemical engineering with gas absorption with chemical reaction. Here, the electrode surface is assimilated to the gas–liquid interface, and the reducing Rh(I) formed at the electrode corresponds to the dissolved gas. This method allows the kinetics of the liquid phase reaction between NAD⁺ and Rh(I) to be estimated and the beneficial effect of NAD⁺ concentration on the reduction current of Rh(III) to be successfully predicted. Moreover, because of the fast kinetics of the liquid phase reaction, the overall mediated regeneration of NADH by the redox Rh couple can be viewed as occurring as the direct reduction of NAD⁺ to NADH. The approach could be applied to other electromediated processes, upon sufficient knowledge of the system physico-chemical specificities.

基于氯（2,2'-联吡啶基）（五甲基环戊二烯基）-铑（III）氯化物络合物-Rh（III）对β-烟酰胺腺嘌呤二核苷酸水合物（NADH）的电介导再生，该手稿描述了一种建模方法通过多相化学工程与气体吸收和化学反应。此处，电极表面与气液界面同化，电极处形成的还原性 Rh(I) 对应于溶解气体。此方法允许NAD之间的液相反应的动力学⁺和Rh（I）进行估计和NAD的有益效果⁺Rh(III) 还原电流的浓度被成功预测。此外，由于液相反应的快速动力学，氧化还原 Rh 对介导的 NADH 整体再生可以看作是 NAD ⁺直接还原为 NADH 的过程。在充分了解系统物理化学特性后，该方法可以应用于其他电介导过程。