PURPOSE The present study aimed to investigate the status and significantly influencing factors of treatment and prognosis perceptions among advanced cancer patients based on patient-reported outcome. METHODS A cross-sectional study was conducted at two tertiary A general hospitals. From June to September 2019, 300 patients were invited and 292 of them participated in this study. Except for 9 invalid questionnaires, 283 pen-paper questionnaires including sociodemographic and clinical characteristics, Chinese Version of Prognosis and Treatment Perception Questionnaire, Herth Hope Index, and Hospital Anxiety and Depression Scale were well completed. Descriptive analysis, Pearson's correlation test, logistic regression analysis, and multiple linear regression analysis were applied for analysis. RESULTS One hundred seventy-five (61.8%) advanced cancer patients reported inaccurate treatment perception. Prognosis perception scored 87.9 ± 13.72 indicating a middle level of prognosis perception. Fourteen (4.9%), 138 (48.8%), and 131 (46.3%) patients presented low, middle, and high prognosis perception levels, respectively. In patients, without spouse and religion beliefs, received chemoradiotherapy, diagnosed as cancer equal to or less than 1 year, and higher hope level were inaccurate treatment perception's risk factors. Younger age, longer diagnosis time, higher educational level, less support for medical expenses payment, receiving chemoradiotherapy, and lower hope level but more anxiety and depression symptoms were positive predictors of prognosis perception. CONCLUSIONS A majority of advanced cancer patients in this study reported inaccurate treatment and middle level of prognosis perception influencing by objective and subjective factors. Clinical interventions could be developed referring these impacting factors originating from patient-reported outcome.

中文翻译：

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晚期癌症患者治疗和预后感知的影响因素：一项横断面研究。

目的 本研究旨在根据患者报告的结果调查晚期癌症患者治疗和预后感知的状况和显着影响因素。方法在两家三甲综合医院进行横断面研究。2019 年 6 月至 2019 年 9 月，共邀请了 300 名患者，其中 292 人参与了本研究。除9份无效问卷外，完成社会人口学及临床特征、中文版预后及治疗认知问卷、Herth希望指数、医院焦虑抑郁量表等283份纸笔问卷。采用描述性分析、皮尔逊相关检验、逻辑回归分析和多元线性回归分析进行分析。结果一百七十五（61。8%) 晚期癌症患者报告的治疗认知不准确。预后感知得分为 87.9 ± 13.72，表明预后感知处于中等水平。14 名 (4.9%)、138 名 (48.8%) 和 131 名 (46.3%) 患者分别表现出低、中、高预后感知水平。在没有配偶和宗教信仰的患者中，接受过放化疗，被诊断为癌症等于或小于1年，希望水平较高是治疗感知不准确的危险因素。年龄越小、诊断时间越长、文化程度越高、医疗费用支付支持越少、接受放化疗、希望水平越低但焦虑抑郁症状越多是预后感知的阳性预测因子。结论 本研究中的大多数晚期癌症患者报告了受客观和主观因素影响的不准确治疗和中等水平的预后感知。可以参考源自患者报告结果的这些影响因素制定临床干预措施。