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Time to resolution of infection in COVID-19 patients: the experience of a tertiary medical center in Israel.
Japanese Journal of Infectious Diseases ( IF 2.2 ) Pub Date : 2021-08-31 , DOI: 10.7883/yoken.jjid.2021.215
Emily Lubart 1, 2 , Gilad Gal 3 , Eliyahu H Mizrahi 1, 2 , Ahuva Tzabary 2 , Ehuda Baumohl 2 , Erica Pinco 2 , Zuhdi Idkiedek 2 , Eisa Haj Ali 2 , Maya Berger 2 , Galina Goltsman 1, 4
Affiliation  

With the coronavirus disease spreading, reports indicated that young patients are usually asymptomatic with a short convalescence period. The current study compares the time to resolution of infection in symptomatic versus asymptomatic patients. Seventy- six patients aged 44.4±23.3 years were admitted to the COVID-19 Unit during the study period. Data was collected from patients’ records. Throat and nasal swabs for the RT-PCR COVID-19 were collected. Time to resolution of infection was defined as the number of days from the date of the first COVID-19 positive outcome to the second consecutive negative PCR results. Most patients showed between 1-6 COVID-19 signs and symptoms (71.1%) and the rest were asymptomatic. No association was found between the time to resolution of infection and the presence of COVID-19 signs and symptoms (symptomatic: Md 10.0 95% CI 8.4-11.6; asymptomatic: Md 15.0 95% CI 10.5-15.5; p=0.54). Age was not correlated with the number of COVID-19 signs and symptoms (r=0.13, p=0.37) and with the time to resolution of infection (r=0.06, p=0.58). In mild to moderate symptomatic patients, the time to resolution of infection from COVID-19 is not different from asymptomatic patients.



中文翻译:

解决 COVID-19 患者感染的时间:以色列一家三级医疗中心的经验。

随着冠状病毒病的蔓延,报告显示年轻患者通常无症状,恢复期较短。目前的研究比较了有症状和无症状患者感染消退的时间。在研究期间,76 名年龄为 44.4±23.3 岁的患者入住 COVID-19 单元。从患者的记录中收集数据。收集了用于 RT-PCR COVID-19 的咽拭子和鼻拭子。感染消退时间定义为从出现第一个 COVID-19 阳性结果之日到第二个连续的 PCR 阴性结果的天数。大多数患者表现出 1-6 种 COVID-19 体征和症状(71.1%),其余患者无症状。没有发现感染消退的时间与 COVID-19 体征和症状(症状:Md 10. 0 95% CI 8.4-11.6;无症状:Md 15.0 95% CI 10.5-15.5;p = 0.54)。年龄与 COVID-19 体征和症状的数量(r=0.13,p=0.37)和感染消退时间(r=0.06,p=0.58)无关。在轻度至中度有症状的患者中,从 COVID-19 感染消退的时间与无症状患者没有区别。

更新日期:2021-08-30
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