ABSTRACT

Coordination of international aphasia research would minimise duplication of effort, support synergistic international activities across languages and multidisciplinary perspectives, and promote high-quality conduct and reporting of aphasia research, thereby increasing the relevance, transparency, and implementation of findings. The Collaboration of Aphasia Trialists (CATs) sought to develop an aphasia research agenda to direct future research activities, based on priorities shared by people with aphasia, family members, and healthcare professionals. Our established international research network spanning 33 countries contributed to this activity. Research literature reporting the priorities of stakeholders was reviewed and synthesized (phase 1). Representatives from Working Groups on Aphasia Assessment & Outcomes, Prognosis & Predictors of Recovery, Effectiveness of Interventions, and Societal Impact & Reintegration participated in a two-day research agenda-setting meeting. The CATs expert panel refined research objectives and identified constituent components of research and methodological developments required to address these research components. The objectives and research components were grouped into overarching themes (phase 2). The resultant list was then circulated to more than 180 CATs members for review, revision, and approval. Consensus on the final aphasia research agenda and roadmap was reached by CATs executive committee (phase 3). The expert panel identified five overarching research themes: (i) evidence-based interventions for people with aphasia, (ii) effective interventions to support those communicating with people with aphasia, (iii) cross-linguistic assessment and core outcomes for aphasia research, (iv) predictors of language recovery, and (v) clinical implementation of research findings. Within these broad themes, 30 research objectives and 91 individual aphasia research components were identified and sequentially ordered. This agenda builds on research priorities identified by people with aphasia and their families, and includes priorities of healthcare professionals and researchers, and will support the rehabilitation and recovery of people with aphasia. Our internationally relevant research agenda promotes rigor in methodology, considers international applicability, synergistic activities, and sharing of resources and expertise.

摘要

国际失语症研究的协调将最大限度地减少重复工作，支持跨语言和多学科视角的协同国际活动，并促进失语症研究的高质量实施和报告，从而提高研究结果的相关性、透明度和实施。失语症试验者合作组织 (CATs) 试图根据失语症患者、家庭成员和医疗保健专业人员共享的优先事项制定失语症研究议程，以指导未来的研究活动。我们建立的跨越 33 个国家的国际研究网络为这项活动做出了贡献。审查和综合了报告利益相关者优先事项的研究文献（第 1 阶段）。失语症评估和结果工作组的代表，预后和 恢复、干预效果和社会影响与重新融合的预测因素参加了为期两天的研究议程设置会议。CATs 专家小组完善了研究目标，并确定了研究的组成部分和解决这些研究组成部分所需的方法发展。目标和研究组成部分分为总体主题（第 2 阶段）。最终清单随后分发给 180 多个 CAT 成员进行审查、修订和批准。CATs 执行委员会就最终失语症研究议程和路线图达成共识（第 3 阶段）。专家小组确定了五个总体研究主题：(i) 对失语症患者的循证干预，(ii) 支持与失语症患者交流的有效干预措施，(iii) 失语症研究的跨语言评估和核心成果，(iv) 语言恢复的预测因素，以及 (v) 研究结果的临床实施。在这些广泛的主题中，确定并按顺序排列了 30 个研究目标和 91 个单独的失语症研究组成部分。该议程以失语症患者及其家人确定的研究重点为基础，包括医疗保健专业人员和研究人员的优先事项，并将支持失语症患者的康复和康复。我们的国际相关研究议程提倡严谨的方法论，考虑国际适用性、协同活动以及资源和专业知识的共享。(v) 研究结果的临床实施。在这些广泛的主题中，确定并按顺序排列了 30 个研究目标和 91 个单独的失语症研究组成部分。该议程以失语症患者及其家人确定的研究重点为基础，包括医疗保健专业人员和研究人员的优先事项，并将支持失语症患者的康复和康复。我们的国际相关研究议程提倡严谨的方法，考虑国际适用性、协同活动以及资源和专业知识的共享。(v) 研究结果的临床实施。在这些广泛的主题中，确定并按顺序排列了 30 个研究目标和 91 个单独的失语症研究组成部分。该议程以失语症患者及其家人确定的研究重点为基础，包括医疗保健专业人员和研究人员的优先事项，并将支持失语症患者的康复和康复。我们的国际相关研究议程提倡严谨的方法，考虑国际适用性、协同活动以及资源和专业知识的共享。并包括医疗保健专业人员和研究人员的优先事项，并将支持失语症患者的康复和康复。我们的国际相关研究议程提倡严谨的方法论，考虑国际适用性、协同活动以及资源和专业知识的共享。并包括医疗保健专业人员和研究人员的优先事项，并将支持失语症患者的康复和康复。我们的国际相关研究议程提倡严谨的方法论，考虑国际适用性、协同活动以及资源和专业知识的共享。