Bioseparation is a crucial process for the obtention of biological products that are essential in daily life, such as medicine and food. At first, the researchers centered their efforts on the optimization of the upstream processes, conducting to high product titer. Afterwards, they turned their attention to improving the downstream processes. Since then, a revolution of technologies has been reported for the recovery, separation, and/or purification of bioproducts. Therefore, this perspective article aims to present the advances, current challenges, and future trends in bioseparation. In this context, a practical approach to summarize the published articles in the Journal of Chemical Technology and Biotechnology regarding this topic is presented; in addition, a classification of, (i) trusted old, (ii) novel, and (iii) evolved technologies is proposed. © 2021 Society of Chemical Industry (SCI).

中文翻译：

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生物分离的进展、当前挑战和未来趋势：对 JCTB 发表论文的透视分析

生物分离是获取日常生活中必不可少的生物产品（如药品和食品）的关键过程。起初，研究人员将精力集中在上游工艺的优化上，以达到高产品滴度。之后，他们将注意力转向改进下游流程。从那时起，据报道，生物产品的回收、分离和/或纯化技术发生了革命。因此，本文旨在介绍生物分离的进展、当前挑战和未来趋势。在此背景下，总结发表在Journal of Chemical Technology and Biotechnology 上的文章的实用方法关于这个主题的介绍；此外，还提出了 (i) 受信任的旧技术、(ii) 新颖和 (iii) 进化技术的分类。© 2021 化学工业协会 (SCI)。