The aim of this research is to employ Gotukola (Centella Asiatica) to prepare multifunctional ZnO nanocrystals through solution combustion synthesis. PXRD pattern reveals the obtained particles belongs to hexagonal wurtzite system . Debye sherrercalculations reveal that the particle sizes were 7, 8 and 11 nm. TEM and SEM images shows that the particles have porous and sponge-like morphology. A sharp peak at 443 nm in PL spectra was observed due to Zn and O-vacancies. FTIR spectra exibits the broad peak caentered at 3441 cm⁻¹ corresponds to the O-H stretching frequencies. Further the catalyst shows excellent photocatalytic activity towards the degradation of environmental pollutants like methylene blue and methyl orange and eosin yellow, and also acts as good free radical scavenger. It effectively inhibits the free radical activity of 1,1-Dipheny-2- picrylhydrazyl (DPPH). It also exhibit the antibacterial activity against the E.coli, P.desmolyticum, P.eruginosa, K.aerogenes, and Aureus pathogenic bacterial strains. ZnO-Nps were tested for their antidiabetic ability, and they showed excellent - glucosidase (IC₅₀ of 95.55 μg/ml) and - amylase (IC₅₀ of 84.00 μg/ml) inhibitory activities. The cytotoxic effects of ZnO Nps on the HeLa cell line were investigated using the MTT test, which revealed a dose-dependent action. The IC₅₀ value was found to be 232 μg/ml, indicating that they have a greater cytotoxic potency. The synthesised nanoparticles also acts as a strong anticoagulant agent. The study demonstrates preparation of multifunctional ZnO Nps using a Solution Combustion Synthesis method that is quick, economical and eco sustainable.

本研究的目的是利用 Gotukola ( Centella Asiatica ) 通过溶液燃烧合成制备多功能 ZnO 纳米晶。PXRD图谱表明所得颗粒属于六方纤锌矿系统。Debye Sherrer 计算表明，粒径为 7、8 和 11 nm。TEM 和 SEM 图像显示颗粒具有多孔和海绵状形态。由于 Zn 和 O 空位，在 PL 光谱中观察到 443 nm 处的尖峰。FTIR 光谱显示了位于 3441 cm ^-1处的宽峰对应于 OH 拉伸频率。此外，该催化剂对亚甲蓝、甲基橙和曙红黄等环境污染物的降解表现出优异的光催化活性，同时也是良好的自由基清除剂。它有效抑制 1,1-Dipheny-2-picrylhydrazyl (DPPH) 的自由基活性。它还表现出对大肠杆菌、P.desmolyticum、P.eruginosa、K.aerogenes和Aureus致病细菌菌株的抗菌活性。测试了 ZnO-Nps 的抗糖尿病能力，它们表现出优异的 - 葡萄糖苷酶 (IC ₅₀为 95.55 μg/ml) 和 - 淀粉酶 (IC ₅₀84.00 μg/ml) 抑制活性。使用 MTT 测试研究了 ZnO Nps 对 HeLa 细胞系的细胞毒性作用，这揭示了剂量依赖性作用。发现IC ₅₀值为232 μg/ml，表明它们具有更大的细胞毒性效力。合成的纳米颗粒还充当强抗凝剂。该研究展示了使用快速、经济和生态可持续的溶液燃烧合成方法制备多功能 ZnO Nps。