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Anti-GABAB receptor encephalitis associated with combined small cell lung carcinoma
Journal of Neuroimmunology ( IF 3.3 ) Pub Date : 2021-08-28 , DOI: 10.1016/j.jneuroim.2021.577705
Chung-Hao Chao, Chun-Che Chu, Yi-Chia Wei, Jing-Ren Tseng, Hong-Shiu Chang

Autoimmune encephalitis with antibodies against the gamma-aminobutyric acid-B receptor is a relatively rare disease. We report a case with characteristic symptoms of limbic encephalitis associated with combined small cell lung carcinoma. The brain magnetic resonance imaging showed bilateral temporal lesions and the photoemission tomography revealed regional heterogenous metabolism across the brain. The double labeling of anti-gamma-aminobutyric acid-B receptor autoantibodies both in the tissues of neuroendocrine and small cell neoplasia was a unique feature of this patient.



中文翻译:

合并小细胞肺癌相关的抗 GABAB 受体脑炎

具有抗 γ-氨基丁酸-B 受体抗体的自身免疫性脑炎是一种相对罕见的疾病。我们报告了一例伴有联合小细胞肺癌的边缘性脑炎特征性症状的病例。脑磁共振成像显示双侧颞叶病变,光电子断层扫描显示整个大脑的区域异质代谢。神经内分泌和小细胞瘤组织中抗 γ-氨基丁酸-B 受体自身抗体的双重标记是该患者的独特特征。

更新日期:2021-08-31
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