当前位置: X-MOL 学术Org. Process Res. Dev. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Scale-Up of a Continuous Manufacturing Process of Edaravone
Organic Process Research & Development ( IF 3.4 ) Pub Date : 2021-08-27 , DOI: 10.1021/acs.oprd.1c00228
Shuhao Zhou 1 , Qingxia Hong 1 , Wenliu Mei 1 , Yan He 2 , Chengjun Wu 1 , Tiemin Sun 1
Affiliation  

Edaravone belongs to a class of brain-protective agents, which can scavenge free radicals. To reduce impurities and improve the yield, a continuous flow production process of edaravone was developed. The synthesis is continuously carried out in two steps. The throughput can reach 11.328 kg/day and the purity of the final product is 99.95%, which are in accordance with the needs of production. This is an efficient and quick production process suitable for industrial production.

中文翻译:

依达拉奉连续生产工艺的放大

依达拉奉属于一类脑保护剂,可以清除自由基。为了减少杂质和提高收率,开发了依达拉奉的连续流生产工艺。合成分两步连续进行。产量可达11​​.328公斤/天,成品纯度99.95%,符合生产需要。这是一种适用于工业生产的高效快捷的生产工艺。
更新日期:2021-09-17
down
wechat
bug