The objective of this study is to gain a better understanding of the metal characteristics, sources, and health risks of children's exposure to PM_2.5 and related metals in children's bedrooms in urban and rural areas. PM_2.5 personal environmental monitoring samplers were used to collect both indoor and outdoor PM_2.5 in urban and rural areas in Taiwan. Al, Cd, Cr, Mn, Pb, V, and Zn were analyzed by inductively coupled plasma mass spectrometry. Source apportionment of metals in PM_2.5 was carried out with factor analysis (FA). Health risk assessment of metals was performed on children via inhalation. The average indoor PM_2.5 concentrations were 11.9 ± 5.2 μg/m³ and 11.9 ± 4.7 μg/m³ in urban and rural areas, respectively. The most predominant metal indoors in urban areas was Al, followed by Zn, Pb, Mn, V, Cr, and Cd, with a similar result in rural areas. The results from FA indicated that traffic emission and oil combustion in the outside environment were major pollution sources to indoor Mn, V, and Zn; corrosion of building material could be a contributor to Al, Cd, and Pb; pollution sources were different to Cr in two areas. The carcinogenic risk for indoor Cr(VI) via inhalation was higher in urban areas (boy: 6.61E-06; girl: 6.18E-06) than that in rural areas (boy: 2.80E-06; girl: 2.62E-06). These findings will help us to further understand the pollution sources, health risks, and control strategies for metals in PM_2.5 in children's bedrooms for reducing adverse health effects, including in rural areas.