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MHC class I molecules co-stimulate NK1.1 signaling and enhance Ca2+ flux in murine NK cells
European Journal of Immunology ( IF 5.4 ) Pub Date : 2021-08-27 , DOI: 10.1002/eji.202048709
Sridharan Ganesan 1 , Petter Höglund 1, 2
Affiliation  

Simultaneous triggering of NK1.1 and MHC class I on NK cells gives a higher Ca2+ flux response compared to triggering the NK1.1 receptor alone. The data suggest a novel costimulatory role for MHC class I molecules on NK cell responses.
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中文翻译:

MHC I 类分子共同刺激 NK1.1 信号传导并增强鼠 NK 细胞中的 Ca2+ 通量

与单独触发 NK1.1 受体相比,在 NK 细胞上同时触发 NK1.1 和 MHC I 类会产生更高的 Ca 2+通量响应。数据表明 MHC I 类分子对 NK 细胞反应具有新的共刺激作用。
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更新日期:2021-10-06
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