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Psoriasis treatment using minimally manipulated umbilical cord-derived mesenchymal stem cells: A case report.
World Journal of Clinical Cases ( IF 1.1 ) Pub Date : 2021-8-28 , DOI: 10.12998/wjcc.v9.i23.6798
Hyunjun Ahn 1 , Sang Yeon Lee 1 , Won-Ju Jung 2 , Jia Pi 1 , Kye-Ho Lee 1
Affiliation  

Psoriasis is a chronic autoimmune disease that usually manifests as a red scaly epidermis, induration, and hyperproliferation of basal keratinocytes. About 2% of the world's population suffers from psoriasis but there are no clear therapeutics yet. Recently, mesenchymal stem cells (MSCs) have been regarded as a therapeutic alternative for autoimmune diseases, as they possess immunosuppressive effects without risks. Human umbilical cord-derived MSCs effectively regulate immune cells and are characterized by low immunogenicity, which has many advantages in treating immune diseases.

中文翻译:

使用最少操作的脐带间充质干细胞治疗银屑病:病例报告。

银屑病是一种慢性自身免疫性疾病,通常表现为红色鳞状表皮、硬结和基底角质形成细胞过度增殖。世界上约有 2% 的人口患有银屑病,但尚无明确的治疗方法。最近,间充质干细胞 (MSCs) 被认为是自身免疫性疾病的治疗替代品,因为它们具有免疫抑制作用而没有风险。人脐带源间充质干细胞有效调节免疫细胞,具有免疫原性低的特点,在治疗免疫疾病方面具有诸多优势。
更新日期:2021-08-28
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