当前位置: X-MOL 学术Pediatr. Dermatol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
CARD14-associated papulosquamous eruption (CAPE) in pediatric patients: Three additional cases and review of the literature
Pediatric Dermatology ( IF 1.5 ) Pub Date : 2021-08-26 , DOI: 10.1111/pde.14779
Cindy P Frare 1 , Alli J Blumstein 2 , Amy S Paller 2 , Lia Pieretti 3 , Keith A Choate 4 , Anne M Bowcock 5 , Margarita Larralde 1, 6
Affiliation  

CARD14-associated papulosquamous eruption (CAPE) is a proposed term that encompasses features ranging from psoriasis to pityriasis rubra pilaris (PRP) in association with CARD14 mutations. The early onset of the disease, prominent facial involvement, family history of an autosomal dominant trait, and poor response to conventional treatment are characteristics of CAPE that distinguish it from classical psoriasis and PRP. We describe the clinical features, family history, and response to therapy in three unrelated children with CAPE and compare these characteristics with those of previously described pediatric patients. Testing for CARD14 mutations in children with early onset of features of psoriasis or pityriasis rubra pilaris and resistance to conventional therapy should be considered.

中文翻译:

儿科患者 CARD14 相关丘疹鳞屑性皮疹 (CAPE):另外三个病例和文献回顾

CARD14相关丘疹鳞屑性皮疹 (CAPE) 是一个提议的术语,包括与CARD14突变相关的从银屑病到毛发红糠疹 (PRP) 的特征。该病的早期发病、明显的面部受累、常染色体显性遗传特征的家族史以及对常规治疗反应不佳是 CAPE 与经典银屑病和 PRP 区别的特征。我们描述了三名不相关的 CAPE 儿童的临床特征、家族史和对治疗的反应,并将这些特征与之前描述的儿科患者的特征进行比较。测试CARD14应考虑早期出现银屑病或毛发红糠疹特征以及对常规治疗耐药的儿童的突变。
更新日期:2021-08-26
down
wechat
bug