Medicinal plants are composed of a rich pool of biomolecules and have been increasingly recognized for their antimicrobial properties; however, increasing concerns have been put on the bioavailability features. Thus, this study is aimed at exploring the synthesis and characterization of silver nanoparticles synthesized by Chenopodium album L. leaf extract and assessing the antifungal activity against Aspergillus terreus Thom. Plant extract was prepared in methanol to synthetize silver nanoparticles, which were then characterized by Scanning Electron Microscopy (SEM), UV-Visible spectroscopy, and particle size analysis. UV-Visible analysis indicated maximum absorption at 378 nm, and an average particle size was observed as 25.6 nm. Oval to hexagonal shape was observed by SEM. Antifungal activity of silver nanoparticles (1, 1.5, 2, 2.5, 3, and 3.5%) was addressed against A. terreus biomass. At 3.5%, silver nanoparticles revealed to be highly effective, leading to 92% retardation in fungus growth. In next phase, various organic fractions, viz., chloroform, n-butanol, n-hexane, and ethyl acetate, were obtained from plant methanol extract, and the corresponding silver nanoparticles were prepared. These fractions were also assessed for antifungal activity, and n-hexane fraction led to 64% inhibition in A. terreus biomass. Following gas chromatography-mass spectrometry (GC-MS), 18 compounds were identified, namely, 1,3-cyclopentadiene-5-(1 methylethylidene and o-xylene), ethyl benzene, octadecane, nonane, decane, 2-methylheptane, n-hexadecane, 2-methylheptane, and eicosane, along with carbonyl compounds (4,4-dimethyl-3-hexanone) and phenols, like stearic acid, propionic acid hydrazide, and 2,4-di-T-butylphenol. These findings proved that C. album silver nanoparticles are highly effective against A. terreus.

中文翻译：

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绿色合成银纳米颗粒作为抗土曲霉的强效抗真菌剂

药用植物由丰富的生物分子组成，其抗菌特性越来越得到认可；然而，人们越来越关注生物利用度特征。因此，本研究旨在探索由藜叶提取物合成的银纳米颗粒的合成和表征，并评估其对土曲霉的抗真菌活性。汤姆。在甲醇中制备植物提取物以合成银纳米颗粒，然后通过扫描电子显微镜 (SEM)、紫外-可见光谱和粒度分析对其进行表征。紫外-可见分析表明在 378 nm 处有最大吸收，观察到的平均粒径为 25.6 nm。通过SEM观察到椭圆形到六边形。银纳米粒子（1、1.5、2、2.5、3和 3.5%）的抗真菌活性针对A. terreus生物质。在 3.5% 时，银纳米粒子显示出非常有效，导致 92% 的真菌生长延迟。在下一阶段，各种有机馏分，即氯仿、正丁醇、n从植物甲醇提取物中提取-己烷和乙酸乙酯，制备相应的银纳米颗粒。这些级分也评估了抗真菌活性，和Ñ己烷馏分导致64％抑制土曲霉的生物量。经气相色谱-质谱联用 (GC-MS)，鉴定出 18 种化合物，即 1,3-环戊二烯-5-（1 甲基亚乙基和邻二甲苯）、乙苯、十八烷、壬烷、癸烷、2-甲基庚烷、n -十六烷、2-甲基庚烷和二十烷，以及羰基化合物（4,4-二甲基-3-己酮）和酚类，如硬脂酸、丙酸酰肼和 2,4-二-叔丁基苯酚。这些发现证明了C. album银纳米颗粒对A. 土星。