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Fertility and breast cancer: A literature review of counseling, preservation options and outcomes
Critical Reviews in Oncology/Hematology ( IF 6.2 ) Pub Date : 2021-08-27 , DOI: 10.1016/j.critrevonc.2021.103461
Santiago Moragón 1 , Raimondo Di Liello 2 , Begoña Bermejo 3 , Cristina Hernando 1 , Ernesto Olcina 4 , Isabel Chirivella 1 , Ana Lluch 3 , Juan Miguel Cejalvo 3 , María Teresa Martínez 1
Affiliation  

Fertility preservation is an important issue in breast cancer patients undergoing oncological treatment. Fertility counseling is a crucial need given the physical and psychological stress experienced by patients.

Cryopreservation of mature oocytes is currently the standard fertility-preserving procedure. Other options such as ovarian tissue preservation or gonadal protection during chemotherapy are still experimental, but have proven effectiveness. Prompt referral to a fertility unit is highly recommended in order to ensure quality of care. In this article, we focus on the different strategies to preserve fertility in breast cancer patients, assessing also the safety of pregnancy and breastfeeding after cancer. A systemic literature review was performed for research articles published in English in PubMed, or as abstracts from the European Society for Medical Oncology (ESMO), San Antonio Breast Cancer Symposium (SABCS) and American Society of Clinical Oncology (ASCO) annual meetings, using the search terms “breast cancer” and “fertility".



中文翻译:

生育和乳腺癌:咨询、保存选择和结果的文献综述

保留生育能力是接受肿瘤治疗的乳腺癌患者的一个重要问题。鉴于患者所经历的生理和心理压力,生育咨询是一项至关重要的需求。

成熟卵母细胞的冷冻保存是目前标准的生育力保存程序。其他选择,例如在化疗期间保留卵巢组织或性腺保护仍处于试验阶段,但已被证明是有效的。强烈建议立即转诊到生育单位,以确保护理质量。在这篇文章中,我们重点关注保护乳腺癌患者生育能力的不同策略,同时评估癌症后怀孕和母乳喂养的安全性。对 PubMed 上以英文发表的研究文章或作为欧洲肿瘤内科学会 (ESMO)、圣安东尼奥乳腺癌研讨会 (SABCS) 和美国临床肿瘤学会 (ASCO) 年会摘要的研究文章进行了系统性文献回顾,使用搜索词“乳腺癌”和“生育力”。

更新日期:2021-08-31
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