Plasma renin and aldosterone concentrations related to endovascular ultrasound renal denervation in the RADIANCE-HTN SOLO trial.,Journal of Hypertension

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Plasma renin and aldosterone concentrations related to endovascular ultrasound renal denervation in the RADIANCE-HTN SOLO trial.
Journal of Hypertension ( IF 4.9 ) Pub Date : 2021-08-25 , DOI: 10.1097/hjh.0000000000002994
Naomi D L Fisher ₁ , Ajay J Kirtane ₂ , Joost Daemen ₃ , Florian Rader ₄ , Melvin D Lobo ₅ , Manish Saxena ₅ , Josephine Abraham ₆ , Roland E Schmieder ₇ , Andrew S P Sharp ₈ , Philippe Gosse ₉ , Lisa Claude ₁₀ , Yang Song ₁₁ , Michel Azizi _{12,

13,

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Affiliation

Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Columbia University Medical Center/New York-Presbyterian Hospital and the Cardiovascular Research Foundation, New York, New York, USA.
Erasmus MC, Department of Cardiology, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Cedars-Sinai Heart Institute, Los Angeles, California, USA.
Barts NIHR Biomedical Research Centre, William Harvey Research Institute, Queen Mary University of London, London, UK.
University of Utah Medical Center, Salt Lake City, Utah, USA.
Nephrology and Hypertension, University Hospital Erlangen, Friedrich Alexander University, Erlangen, Germany.
University Hospital of Wales, Cardiff and University of Exeter, Exeter, UK.
Hôpital Saint-André - CHU, Bordeaux, France.
ReCor Medical, Inc., Palo Alto, California.
Baim Institute for Clinical Research, Boston, Massachusetts, USA.
Université de Paris.
AP-HP, Hôpital Européen Georges-Pompidou, Hypertension Department and DMU CARTE.
INSERM, CIC1418, Paris, France.

The RADIANCE-HTN SOLO trial demonstrated a greater reduction in daytime ambulatory SBP at 2 months by endovascular ultrasound renal denervation than sham procedure. We hypothesized that plasma renin and aldosterone concentrations would be associated with the SBP response to renal denervation.

中文翻译：

RADIANCE-HTN SOLO 试验中与血管内超声去肾神经支配相关的血浆肾素和醛固酮浓度。

RADIANCE-HTN SOLO 试验表明，与假手术相比，血管内超声去肾神经支配在 2 个月时可以更大程度地降低日间动态 SBP。我们假设血浆肾素和醛固酮浓度与 SBP 对肾脏去神经支配的反应有关。

更新日期：2021-08-25

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