A system capable of photoreleasing tyramine has been developed. The photodonor system consists of an isoindole cage of tyramine and a biscyclometalated Ir(III) complex singlet oxygen (¹O₂) photosensitizer. Photoirradiation at a wavelength of 365 nm produces tyramine, as evidenced by mass spectrometry and ¹H NMR spectroscopy. The photorelease proceeds through two steps involving the formation of a Diels–Alder-type [2 + 4] cycloadduct of ¹O₂, followed by the slow and spontaneous decomposition of the adduct into tyramine and 2-benzoylbenzophenon.

中文翻译：

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酪胺的单线态氧响应光释放

已经开发出一种能够光释放酪胺的系统。光供体系统由酪胺的异吲哚笼和双环金属化的 Ir(III) 配合物单线态氧 ( ¹ O ₂ ) 光敏剂组成。质谱和¹ H NMR 光谱证明，在 365 nm 波长下进行光照射会产生酪胺。光释放通过两个步骤进行，包括形成¹ O ₂的 Diels-Alder 型 [2 + 4] 环加合物，然后该加合物缓慢且自发地分解为酪胺和 2-苯甲酰基二苯甲酮。