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Analysis of the temperature influence on thermophysical properties in the three-dimensional numerical modeling of heat transfer in human biological tissue in the presence of a cancerous tumor
Brazilian Journal of Chemical Engineering ( IF 1.2 ) Pub Date : 2021-08-25 , DOI: 10.1007/s43153-021-00144-z
Mário Luis Ferreira da Silva 1 , Andréa Oliveira Souza da Costa 2 , Rudolf Huebner 3
Affiliation  

The proposed work consists of the analysis of the temperature influence on thermophysical properties in the three-dimensional computational numerical simulation of heat transfer in human biological tissue in the presence of a tumor. The tissue consists of layers of muscle, fat, and skin. The tumor was considered in the muscle layer. The Pennes model was used to describe the heat diffusion in the tissues. Two approaches were analyzed, one with constant thermophysical properties and the other with temperature dependent properties. In addition, two distinct cases were analyzed, one in which the tumor is already developed and another where it is still in the development stage. The temperature profile showed small differences between the approaches; however, the difference of the temperature gradient is noteworthy. The model with constant properties tends to overestimate the temperatures and to underestimate the temperature gradients. In general, the lower the temperature levels in the tissues, the greater the differences between the approaches.



中文翻译:

在存在癌性肿瘤的情况下人体生物组织传热三维数值模型中温度对热物理特性的影响分析

拟议的工作包括分析温度对存在肿瘤时人体生物组织传热的三维计算数值模拟中的热物理特性的影响。组织由肌肉、脂肪和皮肤层组成。肿瘤被认为是在肌肉层。Pennes 模型用于描述组织中的热扩散。分析了两种方法,一种具有恒定的热物理特性,另一种具有温度相关特性。此外,还分析了两种不同的病例,一种是肿瘤已经发育,另一种是仍处于发育阶段。温度曲线显示方法之间的差异很小;然而,温度梯度的差异是值得注意的。具有恒定属性的模型倾向于高估温度并低估温度梯度。一般来说,组织中的温度水平越低,方法之间的差异就越大。

更新日期:2021-08-26
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