Guaiacol oligomers were synthesized by enzyme-catalyzed polymerization with laccase as the catalyst. The polymerization procedure in aqueous media was followed by UV–vis spectra. The oligomers were characterized by NMR and MALDI-TOF spectra. The UV–vis spectra observation showed a new peak formed in the range of 380−530 nm indicating that new substances formed. The NMR results indicated that phenolic hydroxyl participated in the polymerization. The MALDI-TOF spectra revealed the weight average polymerization degree of guaiacol oligomers is 10 and the mass of the repeating unit is 122. The thermal stability was studied by TGA/DSC analysis. Guaiacol oligomers were more thermally stable than guaiacol, which can be ascribed to the long π-conjugated chains. Antioxidant behavior based on ABTS⁺ radical showed a concentration-dependent activity and reached a plateau at 800 μg/mL. The prepared guaiacol oligomers displayed antimicrobial activity against Staphylococcus aureus and Escherichia coli, in which the inhibition percentage is up to 99 %.

以漆酶为催化剂，通过酶催化聚合合成愈创木酚低聚物。在水性介质中的聚合过程之后是 UV-vis 光谱。低聚物通过NMR和MALDI-TOF光谱表征。UV-vis 光谱观察显示在 380-530 nm 范围内形成了一个新峰，表明形成了新物质。核磁共振结果表明酚羟基参与了聚合。MALDI-TOF谱显示愈创木酚低聚物的重均聚合度为10，重复单元的质量为122。通过TGA/DSC分析研究热稳定性。愈创木酚低聚物比愈创木酚更热稳定，这可以归因于长π共轭链。基于 ABTS ^{+ 的}抗氧化行为自由基显示出浓度依赖性活性，并在 800 μg/mL 时达到平台。制备的愈创木酚低聚物对金黄色葡萄球菌和大肠杆菌均表现出抗菌活性，抑制率高达99%。