Executing memory-guided behavior requires storage of information about experience and later recall of that information to inform choices. Awake hippocampal replay, when hippocampal neural ensembles briefly reactivate a representation related to prior experience, has been proposed to critically contribute to these memory-related processes. However, it remains unclear whether awake replay contributes to memory function by promoting the storage of past experiences, facilitating planning based on evaluation of those experiences, or both. We designed a dynamic spatial task that promotes replay before a memory-based choice and assessed how the content of replay related to past and future behavior. We found that replay content was decoupled from subsequent choice and instead was enriched for representations of previously rewarded locations and places that had not been visited recently, indicating a role in memory storage rather than in directly guiding subsequent behavior.

执行记忆引导的行为需要存储有关经验的信息，然后再回忆这些信息以告知选择。清醒的海马重放，当海马神经集合短暂地重新激活与先前经验相关的表征时，已被提议对这些与记忆相关的过程做出重要贡献。然而，尚不清楚清醒回放是否通过促进过去经验的存储、基于对这些经验的评估促进计划，或两者兼而有之来促进记忆功能。我们设计了一个动态空间任务，在基于记忆的选择之前促进回放，并评估回放的内容如何与过去和未来的行为相关。